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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
View ORCID ProfileBlagoje Soskic, View ORCID ProfileEddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakic, Jorge Esparza-Gordillo, View ORCID ProfileLara Bossini-Castillo, David F. Tough, Christopher G. C. Larminie, Paola G. Bronson, David Wille, View ORCID ProfileGosia Trynka
doi: https://doi.org/10.1101/566810
Blagoje Soskic
1Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
2Open Targets, Wellcome Genome Campus, Cambridge CB10 1SA, UK
Eddie Cano-Gamez
1Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
2Open Targets, Wellcome Genome Campus, Cambridge CB10 1SA, UK
Deborah J. Smyth
1Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
2Open Targets, Wellcome Genome Campus, Cambridge CB10 1SA, UK
Wendy C. Rowan
3Human Genetics, GlaxoSmithKline R&D, Stevenage SG1 2NY, United Kingdom
Nikolina Nakic
4Functional Genomics, Molecular Science and Technology R&D, GSK Medicines Research Centre, Stevenage, SG1 2NY, UK
Jorge Esparza-Gordillo
5Human genetics, GSK Medicines Research Centre, Stevenage, UK, SG1 2NY, UK
Lara Bossini-Castillo
1Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
David F. Tough
6Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline, Medicines Research Centre, Stevenage SG1 2NY, UK
Christopher G. C. Larminie
5Human genetics, GSK Medicines Research Centre, Stevenage, UK, SG1 2NY, UK
Paola G. Bronson
7Statistical Genetics & Genetic Epidemiology, Biogen, Cambridge, MA, USA
David Wille
8Biostatistics, GSK Medicines Research Centre, Stevenage, UK, SG1 2NY, UK
Gosia Trynka
1Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
2Open Targets, Wellcome Genome Campus, Cambridge CB10 1SA, UK
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Posted March 04, 2019.
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakic, Jorge Esparza-Gordillo, Lara Bossini-Castillo, David F. Tough, Christopher G. C. Larminie, Paola G. Bronson, David Wille, Gosia Trynka
bioRxiv 566810; doi: https://doi.org/10.1101/566810
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakic, Jorge Esparza-Gordillo, Lara Bossini-Castillo, David F. Tough, Christopher G. C. Larminie, Paola G. Bronson, David Wille, Gosia Trynka
bioRxiv 566810; doi: https://doi.org/10.1101/566810
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