Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

Fehintola V. Ajogbasile; Judith U. Oguzie; Paul E. Oluniyi; Philomena Eromon; Jessica Uwanibe; Samar B. Mehta; Katherine J. Siddle; Ikponmwosa Odia; Sarah M. Winnicki; Nosa Akpede; George Akpede; Sylvanus Okogbenin; Bronwyn L. MacInnis; Onikepe A. Folarin; Stephen F. Schaffner; Ephraim Ogbaini-Emovon; Oyewale Tomori; Chikwe Ihekweazu; Pardis C. Sabeti; Christian T. Happi

doi:10.1101/572354

New Results

Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

Fehintola V. Ajogbasile, Judith U. Oguzie, View ORCID ProfilePaul E. Oluniyi, Philomena Eromon, Jessica Uwanibe, Samar B. Mehta, Katherine J. Siddle, Ikponmwosa Odia, Sarah M. Winnicki, Nosa Akpede, George Akpede, Sylvanus Okogbenin, Bronwyn L. MacInnis, Onikepe A. Folarin, Stephen F. Schaffner, Ephraim Ogbaini-Emovon, Oyewale Tomori, Chikwe Ihekweazu, Pardis C. Sabeti, Christian T. Happi

doi: https://doi.org/10.1101/572354

Fehintola V. Ajogbasile

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Judith U. Oguzie

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Paul E. Oluniyi

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Paul E. Oluniyi

Philomena Eromon

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jessica Uwanibe

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Samar B. Mehta

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

4Beth Israel Deaconess Medical Center, Division of Infectious Diseases, Boston, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Katherine J. Siddle

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

5Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ikponmwosa Odia

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sarah M. Winnicki

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Nosa Akpede

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

George Akpede

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sylvanus Okogbenin

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Bronwyn L. MacInnis

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

7Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Onikepe A. Folarin

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stephen F. Schaffner

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

5Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.

7Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ephraim Ogbaini-Emovon

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Oyewale Tomori

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Chikwe Ihekweazu

9Nigerian Centre for Disease Control, Abuja, Nigeria.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Pardis C. Sabeti

3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

5Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.

7Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.

10Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christian T. Happi

1African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer’s University, Ede, Osun State, Nigeria.

2Department of Biological Sciences, College of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeria.

6Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

7Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: happic@run.edu.ng

Abstract
Full Text
Info/History
Metrics
Preview PDF

You do not have access to the full text of this article, the first page of the PDF of this article appears above.

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

View the discussion thread.

PreviousNext

Posted March 10, 2019.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

Fehintola V. Ajogbasile, Judith U. Oguzie, Paul E. Oluniyi, Philomena Eromon, Jessica Uwanibe, Samar B. Mehta, Katherine J. Siddle, Ikponmwosa Odia, Sarah M. Winnicki, Nosa Akpede, George Akpede, Sylvanus Okogbenin, Bronwyn L. MacInnis, Onikepe A. Folarin, Stephen F. Schaffner, Ephraim Ogbaini-Emovon, Oyewale Tomori, Chikwe Ihekweazu, Pardis C. Sabeti, Christian T. Happi

bioRxiv 572354; doi: https://doi.org/10.1101/572354

Share This Article: