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Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
doi: https://doi.org/10.1101/573386
Tapash Jay Sarkar
Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.Department of Applied Physics, Stanford University School of Humanities and Sciences, CA 94305
Marco Quarta
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Shravani Mukherjee
Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.
Alex Colville
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305.
Patrick Paine
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Linda Doan
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Christopher M. Tran
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
Constance R. Chu
Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.VA Palo Alto Health Care System, Palo Alto, CA
Steve Horvath
Department of Human Genetics David Geffen School of Medicine, University of California Los Angeles, CA 90095.Department of Biostatistics, Fielding School of Public Health, UCLA, CA 90095
Nidhi Bhutani
Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.
Thomas A. Rando
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
Vittorio Sebastiano
Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.

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Posted March 18, 2019.
Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
bioRxiv 573386; doi: https://doi.org/10.1101/573386
Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
bioRxiv 573386; doi: https://doi.org/10.1101/573386
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