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Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
doi: https://doi.org/10.1101/573386
Tapash Jay Sarkar
1Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305
2Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.
3Department of Applied Physics, Stanford University School of Humanities and Sciences, CA 94305
Marco Quarta
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
12Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Shravani Mukherjee
7Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.
Alex Colville
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
8Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305.
Patrick Paine
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
12Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Linda Doan
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
12Molecular Medicine Research Institute, Sunnyvale, CA, 94085
Christopher M. Tran
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
Constance R. Chu
7Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.
9VA Palo Alto Health Care System, Palo Alto, CA
Steve Horvath
10Department of Human Genetics David Geffen School of Medicine, University of California Los Angeles, CA 90095.
11Department of Biostatistics, Fielding School of Public Health, UCLA, CA 90095
Nidhi Bhutani
7Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.
Thomas A. Rando
4Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
5Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305
6Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304
Vittorio Sebastiano
1Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305
2Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.
Article usage
Posted March 18, 2019.
Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
bioRxiv 573386; doi: https://doi.org/10.1101/573386
Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano
bioRxiv 573386; doi: https://doi.org/10.1101/573386
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