Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

Tapash Jay Sarkar; Marco Quarta; Shravani Mukherjee; Alex Colville; Patrick Paine; Linda Doan; Christopher M. Tran; Constance R. Chu; Steve Horvath; Nidhi Bhutani; Thomas A. Rando; Vittorio Sebastiano

doi:10.1101/573386

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Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

Tapash Jay Sarkar, Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan, Christopher M. Tran, Constance R. Chu, Steve Horvath, Nidhi Bhutani, Thomas A. Rando, Vittorio Sebastiano

doi: https://doi.org/10.1101/573386

Tapash Jay Sarkar

Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.Department of Applied Physics, Stanford University School of Humanities and Sciences, CA 94305

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Marco Quarta

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Molecular Medicine Research Institute, Sunnyvale, CA, 94085

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Shravani Mukherjee

Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.

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Alex Colville

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305Center for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305.

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Patrick Paine

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Linda Doan

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Christopher M. Tran

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Constance R. Chu

Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.VA Palo Alto Health Care System, Palo Alto, CA

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Steve Horvath

Department of Human Genetics David Geffen School of Medicine, University of California Los Angeles, CA 90095.Department of Biostatistics, Fielding School of Public Health, UCLA, CA 90095

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Nidhi Bhutani

Department of Orthopedic Surgery, Stanford School of Medicine, Sanford, CA 94305.

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Thomas A. Rando

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Vittorio Sebastiano

Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA 94305Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, CA 94305.

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