New Results
The genetic architecture of sporadic and recurrent miscarriage
Triin Laisk, Ana Luiza G Soares, Teresa Ferreira, Jodie N Painter, Samantha Laber, Jonas Bacelis, Chia-Yen Chen, Maarja Lepamets, Kuang Lin, Siyang Liu, Iona Y Millwood, Avinash Ramu, Jennifer Southcombe, Marianne S Andersen, Ling Yang, Christian M Becker, Scott D Gordon, Jonas Bybjerg-Grauholm, Øyvind Helgeland, David M Hougaard, Xin Jin, Stefan Johansson, Julius Juodakis, Christiana Kartsonaki, Viktorija Kukushkina, Lifelines Cohort Study, Penelope A Lind, Andres Metspalu, Grant W Montgomery, Andrew P Morris, Preben B Mortensen, Pål R Njølstad, Dale R Nyholt, Margaret Lippincott, Stephanie Seminara, Andres Salumets, Harold Snieder, Krina Zondervan, Zhengming Chen, Donald F Conrad, Bo Jacobsson, Liming Li, Nicholas G Martin, Benjamin M Neale, Rasmus Nielsen, Robin G Walters, Ingrid Granne, Sarah E Medland, Reedik Mägi, Deborah A Lawlor, Cecilia M Lindgren
doi: https://doi.org/10.1101/575167
Triin Laisk
1Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
3Competence Centre on Health Technologies, Tartu, Estonia
Ana Luiza G Soares
4MRC Integrated Epidemiology Unit at the University of Bristol, Bristol, UK
5Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
Teresa Ferreira
6Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK
Jodie N Painter
7QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Samantha Laber
6Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK
8Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
Jonas Bacelis
9Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Östra, Gothenburg, Sweden
Chia-Yen Chen
10Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
11Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, MA, USA
12Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Maarja Lepamets
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Kuang Lin
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
Siyang Liu
14BGI-Shenzhen, Shenzhen 518083, Guangdong, China
15Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen 2200, Denmark
Iona Y Millwood
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
16Medical Research Council Population Health Research Unit (PHRU), University of Oxford, UK
Avinash Ramu
17Department of Genetics, Washington University in St. Louis, Saint Louis, Missouri, USA
Jennifer Southcombe
18Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Marianne S Andersen
19Department of Endocrinology, Odense University Hospital, Odense, Denmark
Ling Yang
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
16Medical Research Council Population Health Research Unit (PHRU), University of Oxford, UK
Christian M Becker
18Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Scott D Gordon
7QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Jonas Bybjerg-Grauholm
20iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark
21Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Øyvind Helgeland
22Department of Genetics and Bioinformatics, Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, Norway
24KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, N-5020, Norway
David M Hougaard
20iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark
21Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Xin Jin
14BGI-Shenzhen, Shenzhen 518083, Guangdong, China
23School of Medicine, South China University of Technology, Guangzhou 510006, Guangdong, China
Stefan Johansson
24KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, N-5020, Norway
25Department of Medical Genetics, Haukeland University Hospital, Bergen, N-5021, Norway
Julius Juodakis
26Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Christiana Kartsonaki
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
16Medical Research Council Population Health Research Unit (PHRU), University of Oxford, UK
Viktorija Kukushkina
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Lifelines Cohort Study
27Lifelines Cohort, Groningen, the Netherlands
Penelope A Lind
7QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Andres Metspalu
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Grant W Montgomery
28University of Queensland, St Lucia, Queensland, Australia
Andrew P Morris
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
8Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
29Department of Biostatistics, University of Liverpool, Liverpool, UK
Preben B Mortensen
20iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark
30National Centre for Register-Based Research, Aarhus University, Denmark
Pål R Njølstad
24KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, N-5020, Norway
31Department of Pediatrics, Haukeland University Hospital, Bergen, Norway
Dale R Nyholt
32School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Queensland, Australia
Margaret Lippincott
33Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA
Stephanie Seminara
33Reproductive Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA
Andres Salumets
1Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia
3Competence Centre on Health Technologies, Tartu, Estonia
34Institute of Bio- and Translational Medicine, University of Tartu, Tartu, Estonia
35Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Harold Snieder
36Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
Krina Zondervan
8Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
18Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Zhengming Chen
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
Donald F Conrad
17Department of Genetics, Washington University in St. Louis, Saint Louis, Missouri, USA
Bo Jacobsson
9Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Östra, Gothenburg, Sweden
22Department of Genetics and Bioinformatics, Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, Norway
Liming Li
37Department of Epidemiology & Biostatistics, Peking University Health Science Centre, Peking University, Beijing, China
Nicholas G Martin
7QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Benjamin M Neale
10Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
11Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, MA, USA
12Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Rasmus Nielsen
38Department of Integrative Biology, University of California Berkeley, Berkeley, California, USA
39Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark
Robin G Walters
13Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK
16Medical Research Council Population Health Research Unit (PHRU), University of Oxford, UK
Ingrid Granne
18Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, UK
Sarah E Medland
7QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
Reedik Mägi
2Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Deborah A Lawlor
4MRC Integrated Epidemiology Unit at the University of Bristol, Bristol, UK
5Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
40Bristol National Institute of Health Research Biomedical Research Centre, Bristol, UK
Cecilia M Lindgren
6Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK
8Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
41Program in Medical and Population Genetics, Broad Institute, Boston, MA, USA
Posted March 12, 2019.
The genetic architecture of sporadic and recurrent miscarriage
Triin Laisk, Ana Luiza G Soares, Teresa Ferreira, Jodie N Painter, Samantha Laber, Jonas Bacelis, Chia-Yen Chen, Maarja Lepamets, Kuang Lin, Siyang Liu, Iona Y Millwood, Avinash Ramu, Jennifer Southcombe, Marianne S Andersen, Ling Yang, Christian M Becker, Scott D Gordon, Jonas Bybjerg-Grauholm, Øyvind Helgeland, David M Hougaard, Xin Jin, Stefan Johansson, Julius Juodakis, Christiana Kartsonaki, Viktorija Kukushkina, Lifelines Cohort Study, Penelope A Lind, Andres Metspalu, Grant W Montgomery, Andrew P Morris, Preben B Mortensen, Pål R Njølstad, Dale R Nyholt, Margaret Lippincott, Stephanie Seminara, Andres Salumets, Harold Snieder, Krina Zondervan, Zhengming Chen, Donald F Conrad, Bo Jacobsson, Liming Li, Nicholas G Martin, Benjamin M Neale, Rasmus Nielsen, Robin G Walters, Ingrid Granne, Sarah E Medland, Reedik Mägi, Deborah A Lawlor, Cecilia M Lindgren
bioRxiv 575167; doi: https://doi.org/10.1101/575167
The genetic architecture of sporadic and recurrent miscarriage
Triin Laisk, Ana Luiza G Soares, Teresa Ferreira, Jodie N Painter, Samantha Laber, Jonas Bacelis, Chia-Yen Chen, Maarja Lepamets, Kuang Lin, Siyang Liu, Iona Y Millwood, Avinash Ramu, Jennifer Southcombe, Marianne S Andersen, Ling Yang, Christian M Becker, Scott D Gordon, Jonas Bybjerg-Grauholm, Øyvind Helgeland, David M Hougaard, Xin Jin, Stefan Johansson, Julius Juodakis, Christiana Kartsonaki, Viktorija Kukushkina, Lifelines Cohort Study, Penelope A Lind, Andres Metspalu, Grant W Montgomery, Andrew P Morris, Preben B Mortensen, Pål R Njølstad, Dale R Nyholt, Margaret Lippincott, Stephanie Seminara, Andres Salumets, Harold Snieder, Krina Zondervan, Zhengming Chen, Donald F Conrad, Bo Jacobsson, Liming Li, Nicholas G Martin, Benjamin M Neale, Rasmus Nielsen, Robin G Walters, Ingrid Granne, Sarah E Medland, Reedik Mägi, Deborah A Lawlor, Cecilia M Lindgren
bioRxiv 575167; doi: https://doi.org/10.1101/575167
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