Abstract
We present a novel method that yields 1100-fold computational speedup and allows biomedical scientists to interactively adjust alignment parameters in real time to iteratively improve final analytical results. Specifically, the alignment time for a 640 million read human RNA-sequencing dataset is reduced from 19 hours to 1 minute using serverless cloud computing. We provide a graphical interface for the accelerated workflows, thus making our methodology accessible to non-cloud experts.
Competing Interest Statement
Hung - BioDepot LLC: Employment and Ownership. Yeung - BioDepot LLC: Employment and Ownership.
Footnotes
We further improved the execution time of our method, extended our technology to more than one cloud provider, and added an interactive and accessible graphical user interface to our high performance technology.