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Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest
Sangkyun Cho, Manasvita Vashisth, Amal Abbas, Stephanie Majkut, Kenneth Vogel, Yuntao Xia, Irena L. Ivanovska, Jerome Irianto, Manorama Tewari, Kuangzheng Zhu, Elisia D. Tichy, Foteini Mourkioti, Hsin-Yao Tang, Roger A. Greenberg, Benjamin L. Prosser, Dennis E. Discher
doi: https://doi.org/10.1101/583179
Sangkyun Cho
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Manasvita Vashisth
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Amal Abbas
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Stephanie Majkut
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Kenneth Vogel
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Yuntao Xia
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Irena L. Ivanovska
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Jerome Irianto
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Manorama Tewari
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Kuangzheng Zhu
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
Elisia D. Tichy
2Orthopaedic Surgery and Cell & Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Foteini Mourkioti
2Orthopaedic Surgery and Cell & Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Hsin-Yao Tang
3Center for Systems and Computational Biology, Wistar Institute, Philadelphia, PA 19104, USA
Roger A. Greenberg
4Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Benjamin L. Prosser
5Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Dennis E. Discher
1Molecular & Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA 19104, USA
2Orthopaedic Surgery and Cell & Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
4Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
5Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
6Penn Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
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Posted March 20, 2019.
Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest
Sangkyun Cho, Manasvita Vashisth, Amal Abbas, Stephanie Majkut, Kenneth Vogel, Yuntao Xia, Irena L. Ivanovska, Jerome Irianto, Manorama Tewari, Kuangzheng Zhu, Elisia D. Tichy, Foteini Mourkioti, Hsin-Yao Tang, Roger A. Greenberg, Benjamin L. Prosser, Dennis E. Discher
bioRxiv 583179; doi: https://doi.org/10.1101/583179
Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest
Sangkyun Cho, Manasvita Vashisth, Amal Abbas, Stephanie Majkut, Kenneth Vogel, Yuntao Xia, Irena L. Ivanovska, Jerome Irianto, Manorama Tewari, Kuangzheng Zhu, Elisia D. Tichy, Foteini Mourkioti, Hsin-Yao Tang, Roger A. Greenberg, Benjamin L. Prosser, Dennis E. Discher
bioRxiv 583179; doi: https://doi.org/10.1101/583179
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