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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders
View ORCID ProfileEnda M Byrne, Zhihong Zhu, Ting Qi, Nathan G Skene, Julien Bryois, Antonio F Pardinas, Eli Stahl, Jordan W Smoller, Marcella Rietschel, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Michael J Owen, James T.R. Walters, Michael C O’Donovan, John G McGrath, Jens Hjerling-Leffler, Patrick F Sullivan, Michael E Goddard, Peter M Visscher, View ORCID ProfileJian Yang, View ORCID ProfileNaomi R Wray
doi: https://doi.org/10.1101/592899
Enda M Byrne
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
Zhihong Zhu
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
Ting Qi
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
Nathan G Skene
2Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Julien Bryois
3Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Antonio F Pardinas
4MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK
Eli Stahl
5Icahn School of Medicine at Mount Sinai, New York, NY, USA
Jordan W Smoller
6Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA
7Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA
8Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
9Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Marcella Rietschel
10Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg
Michael J Owen
4MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK
James T.R. Walters
4MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK
Michael C O’Donovan
4MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK
John G McGrath
11Queensland Brain Institute, University of Queensland, Brisbane, Australia
12Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia
13National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark
Jens Hjerling-Leffler
2Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Patrick F Sullivan
3Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
14Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, USA
15Department of Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7264, USA
Michael E Goddard
16Faculty of Veterinary and Agricultural Science, University of Melbourne, Parkville, Victoria, Australia
17Biosciences Research Division, Department of Economic Development, Jobs, Transport and Resources, Bundoora, Victoria, Australia
Peter M Visscher
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
11Queensland Brain Institute, University of Queensland, Brisbane, Australia
Jian Yang
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
11Queensland Brain Institute, University of Queensland, Brisbane, Australia
Naomi R Wray
1Institute for Molecular Biosciences, University of Queensland, Brisbane, Australia
11Queensland Brain Institute, University of Queensland, Brisbane, Australia
Posted March 31, 2019.
Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders
Enda M Byrne, Zhihong Zhu, Ting Qi, Nathan G Skene, Julien Bryois, Antonio F Pardinas, Eli Stahl, Jordan W Smoller, Marcella Rietschel, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Michael J Owen, James T.R. Walters, Michael C O’Donovan, John G McGrath, Jens Hjerling-Leffler, Patrick F Sullivan, Michael E Goddard, Peter M Visscher, Jian Yang, Naomi R Wray
bioRxiv 592899; doi: https://doi.org/10.1101/592899
Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders
Enda M Byrne, Zhihong Zhu, Ting Qi, Nathan G Skene, Julien Bryois, Antonio F Pardinas, Eli Stahl, Jordan W Smoller, Marcella Rietschel, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Michael J Owen, James T.R. Walters, Michael C O’Donovan, John G McGrath, Jens Hjerling-Leffler, Patrick F Sullivan, Michael E Goddard, Peter M Visscher, Jian Yang, Naomi R Wray
bioRxiv 592899; doi: https://doi.org/10.1101/592899
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