A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Jorge L. Del-Aguila; Zeran Li; Umber Dube; Kathie A. Mihindukulasuriya; John P Budde; Maria Victoria Fernandez; Laura Ibanez; Joseph Bradley; Fengxian Wang; Kristy Bergmann; Richard Davenport; John C. Morris; David M. Holtzman; Richard J. Perrin; Bruno A. Benitez; Joseph Dougherty; Carlos Cruchaga; Oscar Harari

doi:10.1101/593756

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A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Jorge L. Del-Aguila, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P Budde, Maria Victoria Fernandez, Laura Ibanez, Joseph Bradley, Fengxian Wang, Kristy Bergmann, Richard Davenport, John C. Morris, David M. Holtzman, Richard J. Perrin, Bruno A. Benitez, View ORCID ProfileJoseph Dougherty, Carlos Cruchaga, Oscar Harari

doi: https://doi.org/10.1101/593756

Jorge L. Del-Aguila

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USANeuroGenomics and Informatics, Department of Psychiatry Washington University in St. Louis

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Zeran Li

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Umber Dube

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Kathie A. Mihindukulasuriya

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USANeuroGenomics and Informatics, Department of Psychiatry Washington University in St. Louis

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John P Budde

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Maria Victoria Fernandez

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Laura Ibanez

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Joseph Bradley

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Fengxian Wang

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Kristy Bergmann

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA

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Richard Davenport

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA

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John C. Morris

Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USAKnight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USADepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA

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David M. Holtzman

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Richard J. Perrin

Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USAKnight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USADepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA

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Bruno A. Benitez

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USANeuroGenomics and Informatics, Department of Psychiatry Washington University in St. Louis

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Joseph Dougherty

Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA

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ORCID record for Joseph Dougherty

Carlos Cruchaga

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USAKnight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USANeuroGenomics and Informatics, Department of Psychiatry Washington University in St. Louis

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For correspondence: cruchagac@wustl.edu harario@wustl.edu

Oscar Harari

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USAHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USAKnight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USANeuroGenomics and Informatics, Department of Psychiatry Washington University in St. Louis

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For correspondence: cruchagac@wustl.edu harario@wustl.edu

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