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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
Carlos J. Díaz Osterman, Duygu Ozmadenci, Elizabeth G. Kleinschmidt, Kristin N. Taylor, Allison M. Barrie, Shulin Jiang, Lisa M. Bean, Florian J. Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A. Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M. Mark, Guorong Xu, Kathleen M. Fisch, Vihren N. Kolev, David T. Weaver, Jonathan A. Pachter, Balázs Győrffy, Michael T. McHale, Denise C. Connolly, Alfredo Molinolo, View ORCID ProfileDwayne G. Stupack, View ORCID ProfileDavid D. Schlaepfer
doi: https://doi.org/10.1101/594184
Carlos J. Díaz Osterman
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Duygu Ozmadenci
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Elizabeth G. Kleinschmidt
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Kristin N. Taylor
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Allison M. Barrie
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Shulin Jiang
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Lisa M. Bean
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Florian J. Sulzmaier
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Christine Jean
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Isabelle Tancioni
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Kristen Anderson
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Sean Uryu
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Edward A. Cordasco
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Jian Li
2State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University
Xiao Lei Chen
2State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University
Guo Fu
2State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University
Marjaana Ojalill
3Department of Biochemistry, University of Turku, Finland
Pekka Rappu
3Department of Biochemistry, University of Turku, Finland
Jyrki Heino
3Department of Biochemistry, University of Turku, Finland
Adam M. Mark
4Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, CA 92093
Guorong Xu
4Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, CA 92093
Kathleen M. Fisch
4Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, CA 92093
Vihren N. Kolev
5Verastem Oncology, Needham, MA, 02494
David T. Weaver
5Verastem Oncology, Needham, MA, 02494
Jonathan A. Pachter
5Verastem Oncology, Needham, MA, 02494
Balázs Győrffy
6Institute of Enzymology, Hungarian Academy of Sciences, and Semmelweis University 2nd Dept. of Pediatrics, Budapest, Hungary
Michael T. McHale
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Denise C. Connolly
7Fox Chase Cancer Center, Philadelphia, PA 19111
Alfredo Molinolo
8Department of Pathology, Moores UCSD Cancer Center, La Jolla, CA 92093
Dwayne G. Stupack
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
David D. Schlaepfer
1Department of Obstetrics, Gynecology, and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, CA 92093
Article usage
Posted March 30, 2019.
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
Carlos J. Díaz Osterman, Duygu Ozmadenci, Elizabeth G. Kleinschmidt, Kristin N. Taylor, Allison M. Barrie, Shulin Jiang, Lisa M. Bean, Florian J. Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A. Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M. Mark, Guorong Xu, Kathleen M. Fisch, Vihren N. Kolev, David T. Weaver, Jonathan A. Pachter, Balázs Győrffy, Michael T. McHale, Denise C. Connolly, Alfredo Molinolo, Dwayne G. Stupack, David D. Schlaepfer
bioRxiv 594184; doi: https://doi.org/10.1101/594184
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
Carlos J. Díaz Osterman, Duygu Ozmadenci, Elizabeth G. Kleinschmidt, Kristin N. Taylor, Allison M. Barrie, Shulin Jiang, Lisa M. Bean, Florian J. Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A. Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M. Mark, Guorong Xu, Kathleen M. Fisch, Vihren N. Kolev, David T. Weaver, Jonathan A. Pachter, Balázs Győrffy, Michael T. McHale, Denise C. Connolly, Alfredo Molinolo, Dwayne G. Stupack, David D. Schlaepfer
bioRxiv 594184; doi: https://doi.org/10.1101/594184
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