A sparse EEG-informed fMRI model for hybrid EEG-fMRI neurofeedback prediction

ABSTRACT

Measures of brain activity through functional magnetic resonance imaging (fMRI) or Electroencephalography (EEG), two complementary modalities, are ground solutions in the context of neuro-feedback (NF) mechanisms for brain rehabilitation protocols. While NF-EEG (real-time neurofeedback scores computed from EEG signals) have been explored for a very long time, NF-fMRI (real-time neurofeedback scores computed from fMRI signals) appeared more recently and provides more robust results and more specific brain training. Using simultaneously fMRI and EEG for bi-modal neurofeedback sessions (NF-EEG-fMRI, real-time neurofeedback scores computed from fMRI and EEG) is very promising to devise brain rehabilitation protocols. However, fMRI is cumbersome and more exhausting for patients. The original contribution of this paper concerns the prediction of bi-modal NF scores from EEG recordings only, using a training phase where EEG signals as well as the NF-EEG and NF-fMRI scores are available. We propose a sparse regression model able to exploit EEG only to predict NF-fMRI or NF-EEG-fMRI in motor imagery tasks. We compared different NF-predictors steaming from the proposed model. We showed that predicting NF-fMRI scores from EEG signals adds information to NF-EEG scores and significantly improve the correlation with bi-modal NF sessions, compared to classical NF-EEG scores.