Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

Gabriel Sturm; Andres Cardenas; Marie-Abèle Bind; Steve Horvath; Shuang Wang; Yunzhang Wang; Sara Hägg; Michio Hirano; Martin Picard

doi:10.1101/605295

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Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

View ORCID ProfileGabriel Sturm, Andres Cardenas, Marie-Abèle Bind, Steve Horvath, Shuang Wang, Yunzhang Wang, Sara Hägg, Michio Hirano, Martin Picard

doi: https://doi.org/10.1101/605295

Gabriel Sturm

1Department of Psychiatry, Division of Behavioral Medicine, Columbia University Medical Center, New York, NY, 10032, USA

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ORCID record for Gabriel Sturm

Andres Cardenas

2Division of Environmental Health Sciences, University of California, Berkeley, School of Public Health, Berkeley, CA 94720, USA

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Marie-Abèle Bind

3Department of Statistics, Harvard University, Cambridge, MA 02138, USA

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Steve Horvath

4Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA

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Shuang Wang

5Department of Biostatistics, Mailman School of Public Health, Columbia University Medical Center, New York, NY, 10032, USA

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Yunzhang Wang

6Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels Väg 12A, 171 77 Stockholm, Sweden

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Sara Hägg

6Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels Väg 12A, 171 77 Stockholm, Sweden

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Michio Hirano

7Department of Neurology, H. Houston Merritt Center, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, NY, 10032, USA

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Martin Picard

1Department of Psychiatry, Division of Behavioral Medicine, Columbia University Medical Center, New York, NY, 10032, USA

7Department of Neurology, H. Houston Merritt Center, Columbia Translational Neuroscience Initiative, Columbia University Medical Center, New York, NY, 10032, USA

8Columbia Aging Center, Columbia University Mailman School of Public Health, New York, NY, 10032, USA

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For correspondence: martin.picard@columbia.edu

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Posted April 10, 2019.

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Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

Gabriel Sturm, Andres Cardenas, Marie-Abèle Bind, Steve Horvath, Shuang Wang, Yunzhang Wang, Sara Hägg, Michio Hirano, Martin Picard

bioRxiv 605295; doi: https://doi.org/10.1101/605295

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Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

Gabriel Sturm, Andres Cardenas, Marie-Abèle Bind, Steve Horvath, Shuang Wang, Yunzhang Wang, Sara Hägg, Michio Hirano, Martin Picard

bioRxiv 605295; doi: https://doi.org/10.1101/605295

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