New Results
A reference map of the human protein interactome
View ORCID ProfileKatja Luck, Dae-Kyum Kim, View ORCID ProfileLuke Lambourne, View ORCID ProfileKerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Cote, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, View ORCID ProfileTong Hao, Janusz Rak, Jan Tavernier, Vincent Tropepe, View ORCID ProfileDavid E. Hill, View ORCID ProfileMarc Vidal, View ORCID ProfileFrederick P. Roth, View ORCID ProfileMichael A. Calderwood
doi: https://doi.org/10.1101/605451
Katja Luck
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Dae-Kyum Kim
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Luke Lambourne
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Kerstin Spirohn
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Bridget E. Begg
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Wenting Bian
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Ruth Brignall
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Tiziana Cafarelli
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Francisco J. Campos-Laborie
7Cancer Research Center (CiC-IBMCC, CSIC/USAL), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain
8Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
Benoit Charloteaux
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Dongsic Choi
9The Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Atina G. Cote
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Meaghan Daley
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Steven Deimling
10Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada
Alice Desbuleux
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
11Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium
Amélie Dricot
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Marinella Gebbia
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Madeleine F. Hardy
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Nishka Kishore
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Jennifer J. Knapp
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
István A. Kovács
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
12Network Science Institute, Northeastern University, Boston, MA, USA
13Wigner Research Centre for Physics, Institute for Solid State Physics and Optics, Budapest, Hungary
Irma Lemmens
14Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium
15Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
Miles W. Mee
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Joseph C. Mellor
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
17seqWell, Inc. Beverly MA, USA
Carl Pollis
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Carles Pons
18Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain
Aaron D. Richardson
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Sadie Schlabach
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Bridget Teeking
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Anupama Yadav
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Mariana Babor
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Dawit Balcha
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Omer Basha
19Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
20National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Christian Bowman-Colin
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Suet-Feung Chin
21CRUK Cambridge Institute, University of Cambridge, Cambridge, UK
Soon Gang Choi
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Claudia Colabella
22Department of Pharmaceutical Sciences, University of Perugia, Italy
23Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche “Togo Rosati”, Perugia, Italy
Georges Coppin
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
11Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium
Cassandra D’Amata
10Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada
David De Ridder
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Steffi De Rouck
14Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium
15Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
Miquel Duran-Frigola
18Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain
Hanane Ennajdaoui
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Florian Goebels
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Liana Goehring
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Anjali Gopal
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Ghazal Haddad
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Elodie Hatchi
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Mohamed Helmy
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Yves Jacob
24Département de Virologie, Unité de Génétique Moléculaire des Virus à ARN (GMVR), Institut Pasteur, UMR3569, Centre National de la Recherche Scientifique (CNRS), Paris, France
25Université Paris Diderot, Paris, France
Yoseph Kassa
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Serena Landini
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Roujia Li
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Natascha van Lieshout
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Andrew MacWilliams
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Dylan Markey
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Joseph N. Paulson
26Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA
27Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
28Department of Biostatistics, Product Development, Genentech Inc., South San Francisco, CA, USA
Sudharshan Rangarajan
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
John Rasla
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Ashyad Rayhan
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Thomas Rolland
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Adriana San-Miguel
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Yun Shen
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Dayag Sheykhkarimli
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Gloria M. Sheynkman
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Eyal Simonovsky
19Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
20National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Murat Taşan
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Alexander Tejeda
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Jean-Claude Twizere
11Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium
Yang Wang
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Robert J. Weatheritt
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
Jochen Weile
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Yu Xia
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
29Department of Bioengineering, McGill University, Montreal, QC, Canada
Xinping Yang
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Esti Yeger-Lotem
19Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
20National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Quan Zhong
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
30Department of Biological Sciences, Wright State University, Dayton, OH, USA
Patrick Aloy
18Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain
31Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain
Gary D. Bader
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
Javier De Las Rivas
7Cancer Research Center (CiC-IBMCC, CSIC/USAL), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain
8Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
Suzanne Gaudet
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Tong Hao
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Janusz Rak
9The Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Jan Tavernier
14Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium
15Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
Vincent Tropepe
10Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada
David E. Hill
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Marc Vidal
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
Frederick P. Roth
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
16Department of Computer Science, University of Toronto, Toronto, ON, Canada
32Canadian Institute for Advanced Research (CIFAR), Toronto, ON, Canada
Michael A. Calderwood
1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Article Information
History
- April 19, 2019.
Article Versions
- Version 1 (April 10, 2019 - 22:35).
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Katja Luck1,2,3,33,
- Dae-Kyum Kim1,4,5,6,33,
- Luke Lambourne1,2,3,33,
- Kerstin Spirohn1,2,3,33,
- Bridget E. Begg1,2,3,
- Wenting Bian1,2,3,
- Ruth Brignall1,2,3,
- Tiziana Cafarelli1,2,3,
- Francisco J. Campos-Laborie7,8,
- Benoit Charloteaux1,2,3,
- Dongsic Choi9,
- Atina G. Cote1,4,5,6,
- Meaghan Daley1,2,3,
- Steven Deimling10,
- Alice Desbuleux1,2,3,11,
- Amélie Dricot1,2,3,
- Marinella Gebbia1,4,5,6,
- Madeleine F. Hardy1,2,3,
- Nishka Kishore1,4,5,6,
- Jennifer J. Knapp1,4,5,6,
- István A. Kovács1,12,13,
- Irma Lemmens14,15,
- Miles W. Mee4,5,16,
- Joseph C. Mellor1,4,5,6,17,
- Carl Pollis1,2,3,
- Carles Pons18,
- Aaron D. Richardson1,2,3,
- Sadie Schlabach1,2,3,
- Bridget Teeking1,2,3,
- Anupama Yadav1,2,3,
- Mariana Babor1,4,5,6,
- Dawit Balcha1,2,3,
- Omer Basha19,20,
- Christian Bowman-Colin2,3,
- Suet-Feung Chin21,
- Soon Gang Choi1,2,3,
- Claudia Colabella22,23,
- Georges Coppin1,2,3,11,
- Cassandra D’Amata10,
- David De Ridder1,2,3,
- Steffi De Rouck14,15,
- Miquel Duran-Frigola18,
- Hanane Ennajdaoui1,4,5,6,
- Florian Goebels4,5,16,
- Liana Goehring2,3,
- Anjali Gopal1,4,5,6,
- Ghazal Haddad1,4,5,6,
- Elodie Hatchi2,3,
- Mohamed Helmy4,5,16,
- Yves Jacob24,25,
- Yoseph Kassa1,2,3,
- Serena Landini2,3,
- Roujia Li1,4,5,6,
- Natascha van Lieshout1,4,5,6,
- Andrew MacWilliams1,2,3,
- Dylan Markey1,2,3,
- Joseph N. Paulson26,27,28,
- Sudharshan Rangarajan1,2,3,
- John Rasla1,2,3,
- Ashyad Rayhan1,4,5,6,
- Thomas Rolland1,2,3,
- Adriana San-Miguel1,2,3,
- Yun Shen1,2,3,
- Dayag Sheykhkarimli1,4,5,6,
- Gloria M. Sheynkman1,2,3,
- Eyal Simonovsky19,20,
- Murat Taşan1,4,5,6,16,
- Alexander Tejeda1,2,3,
- Jean-Claude Twizere11,
- Yang Wang1,2,3,
- Robert J. Weatheritt4,
- Jochen Weile1,4,5,6,16,
- Yu Xia1,29,
- Xinping Yang1,2,3,
- Esti Yeger-Lotem19,20,
- Quan Zhong1,2,3,30,
- Patrick Aloy18,31,
- Gary D. Bader4,5,16,
- Javier De Las Rivas7,8,
- Suzanne Gaudet1,2,3,
- Tong Hao1,2,3,
- Janusz Rak9,
- Jan Tavernier14,15,
- Vincent Tropepe10,
- David E. Hill1,2,3,*,
- Marc Vidal1,2,*,
- Frederick P. Roth1,4,5,6,16,32,* and
- Michael A. Calderwood1,2,3,*
- 1Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA
- 2Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
- 3Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
- 4The Donnelly Centre, University of Toronto, Toronto, ON, Canada
- 5Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
- 6Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
- 7Cancer Research Center (CiC-IBMCC, CSIC/USAL), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain
- 8Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
- 9The Research Institute of the McGill University Health Centre, Montreal, QC, Canada
- 10Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada
- 11Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium
- 12Network Science Institute, Northeastern University, Boston, MA, USA
- 13Wigner Research Centre for Physics, Institute for Solid State Physics and Optics, Budapest, Hungary
- 14Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium
- 15Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
- 16Department of Computer Science, University of Toronto, Toronto, ON, Canada
- 17seqWell, Inc. Beverly MA, USA
- 18Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain
- 19Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
- 20National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel
- 21CRUK Cambridge Institute, University of Cambridge, Cambridge, UK
- 22Department of Pharmaceutical Sciences, University of Perugia, Italy
- 23Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche “Togo Rosati”, Perugia, Italy
- 24Département de Virologie, Unité de Génétique Moléculaire des Virus à ARN (GMVR), Institut Pasteur, UMR3569, Centre National de la Recherche Scientifique (CNRS), Paris, France
- 25Université Paris Diderot, Paris, France
- 26Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA
- 27Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
- 28Department of Biostatistics, Product Development, Genentech Inc., South San Francisco, CA, USA
- 29Department of Bioengineering, McGill University, Montreal, QC, Canada
- 30Department of Biological Sciences, Wright State University, Dayton, OH, USA
- 31Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain
- 32Canadian Institute for Advanced Research (CIFAR), Toronto, ON, Canada
- ↵* Correspondence and requests for materials should be addressed to M.A.C., F.P.R., M.V., or D.E.H. e-mail: michael_calderwood{at}dfci.harvard.edu; fritz.roth{at}utoronto.ca; marc_vidal{at}dfci.harvard.edu; david_hill{at}dfci.harvard.edu
↵33 These authors contributed equally: Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn.
Posted April 19, 2019.
A reference map of the human protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Cote, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, Vincent Tropepe, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
bioRxiv 605451; doi: https://doi.org/10.1101/605451
A reference map of the human protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Cote, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, Vincent Tropepe, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
bioRxiv 605451; doi: https://doi.org/10.1101/605451
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