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Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ macrophages
View ORCID ProfileAnthony J. Covarrubias, Jose Alberto Lopez-Dominguez, Rosalba Perrone, Abhijit Kale, John Newman, Shankar S. Iyer, Mark S. Schmidt, Herbert G. Kasler, Kyong-Oh Shin, Yong-Moon Lee, Issam Ben-Sahra, Melanie Ott, Charles Brenner, Judith Campisi, Eric Verdin
doi: https://doi.org/10.1101/609438
Anthony J. Covarrubias
1Buck Institute for Research on Aging, Novato, CA 94945, USA
2UCSF Department of Medicine, San Francisco, CA 94158, USA
Jose Alberto Lopez-Dominguez
1Buck Institute for Research on Aging, Novato, CA 94945, USA
Rosalba Perrone
1Buck Institute for Research on Aging, Novato, CA 94945, USA
Abhijit Kale
1Buck Institute for Research on Aging, Novato, CA 94945, USA
John Newman
1Buck Institute for Research on Aging, Novato, CA 94945, USA
2UCSF Department of Medicine, San Francisco, CA 94158, USA
Shankar S. Iyer
4Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Mark S. Schmidt
6Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Herbert G. Kasler
1Buck Institute for Research on Aging, Novato, CA 94945, USA
Kyong-Oh Shin
7College of Pharmacy, Chungbuk National University, Cheongju 28644, Republic of Korea Kyong-Oh Shin, current address: Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea
Yong-Moon Lee
7College of Pharmacy, Chungbuk National University, Cheongju 28644, Republic of Korea Kyong-Oh Shin, current address: Department of Food Science and Nutrition, Hallym University, Chuncheon 24252, Republic of Korea
Issam Ben-Sahra
5Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL 60607, USA
Melanie Ott
3Gladstone Institutes, Virology and Immunology, San Francisco, CA 94158, USA
Charles Brenner
6Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Judith Campisi
1Buck Institute for Research on Aging, Novato, CA 94945, USA
Eric Verdin
1Buck Institute for Research on Aging, Novato, CA 94945, USA
2UCSF Department of Medicine, San Francisco, CA 94158, USA
Posted April 17, 2019.
Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ macrophages
Anthony J. Covarrubias, Jose Alberto Lopez-Dominguez, Rosalba Perrone, Abhijit Kale, John Newman, Shankar S. Iyer, Mark S. Schmidt, Herbert G. Kasler, Kyong-Oh Shin, Yong-Moon Lee, Issam Ben-Sahra, Melanie Ott, Charles Brenner, Judith Campisi, Eric Verdin
bioRxiv 609438; doi: https://doi.org/10.1101/609438
Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ macrophages
Anthony J. Covarrubias, Jose Alberto Lopez-Dominguez, Rosalba Perrone, Abhijit Kale, John Newman, Shankar S. Iyer, Mark S. Schmidt, Herbert G. Kasler, Kyong-Oh Shin, Yong-Moon Lee, Issam Ben-Sahra, Melanie Ott, Charles Brenner, Judith Campisi, Eric Verdin
bioRxiv 609438; doi: https://doi.org/10.1101/609438
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