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Low Dose Ionizing Radiation Strongly Stimulates Insertional Mutagenesis in a γH2AX Dependent Manner
View ORCID ProfileAlex N. Zelensky, Mascha Schoonakker, Inger Brandsma, View ORCID ProfileMarcel Tijsterman, View ORCID ProfileDik C. van Gent, Jeroen Essers, View ORCID ProfileRoland Kanaar
doi: https://doi.org/10.1101/614040
Alex N. Zelensky
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
2Oncode Institute, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Mascha Schoonakker
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Inger Brandsma
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Marcel Tijsterman
3Human Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
Dik C. van Gent
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
2Oncode Institute, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Jeroen Essers
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
4Department of Radiation Oncology, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
5Department of Vascular Surgery, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Roland Kanaar
1Department of Molecular Genetics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
2Oncode Institute, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Article usage
Posted June 11, 2019.
Low Dose Ionizing Radiation Strongly Stimulates Insertional Mutagenesis in a γH2AX Dependent Manner
Alex N. Zelensky, Mascha Schoonakker, Inger Brandsma, Marcel Tijsterman, Dik C. van Gent, Jeroen Essers, Roland Kanaar
bioRxiv 614040; doi: https://doi.org/10.1101/614040
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