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Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

Emma J. Gehrke, Xiafei Zhang, Sheila M. Pimentel-Elardo, Andrew R. Johnson, Christiaan A. Rees, Stephanie E. Jones, Hindra, Sebastian S. Gehrke, Sonya Turvey, Suzanne Boursalie, Jane E. Hill, Erin E. Carlson, Justin R. Nodwell, View ORCID ProfileMarie A. Elliot
doi: https://doi.org/10.1101/614727
Emma J. Gehrke
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Xiafei Zhang
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Sheila M. Pimentel-Elardo
3Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
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Andrew R. Johnson
4Department of Chemistry, Indiana University, Bloomington, Indiana, USA
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Christiaan A. Rees
6Geisel School of Medicine and Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
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Stephanie E. Jones
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Hindra
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Sebastian S. Gehrke
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
5Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario Canada
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Sonya Turvey
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Suzanne Boursalie
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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Jane E. Hill
6Geisel School of Medicine and Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
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Erin E. Carlson
4Department of Chemistry, Indiana University, Bloomington, Indiana, USA
7Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA
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Justin R. Nodwell
3Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
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Marie A. Elliot
1Department of Biology, McMaster University, Hamilton, Ontario, Canada
2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
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  • ORCID record for Marie A. Elliot
  • For correspondence: melliot@mcmaster.ca
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Article Information

doi 
https://doi.org/10.1101/614727
History 
  • April 22, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Emma J. Gehrke1,2,
  2. Xiafei Zhang1,2,
  3. Sheila M. Pimentel-Elardo3,
  4. Andrew R. Johnson4,
  5. Christiaan A. Rees6,
  6. Stephanie E. Jones1,2,
  7. Hindra1,2,
  8. Sebastian S. Gehrke2,5,
  9. Sonya Turvey1,2,
  10. Suzanne Boursalie1,2,
  11. Jane E. Hill6,
  12. Erin E. Carlson4,7,
  13. Justin R. Nodwell3 and
  14. Marie A. Elliot1,2,*
  1. 1Department of Biology, McMaster University, Hamilton, Ontario, Canada
  2. 2Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
  3. 3Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
  4. 4Department of Chemistry, Indiana University, Bloomington, Indiana, USA
  5. 5Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario Canada
  6. 6Geisel School of Medicine and Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA
  7. 7Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA
  1. ↵*Corresponding author, E-mail: melliot{at}mcmaster.ca
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Posted April 22, 2019.
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Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2
Emma J. Gehrke, Xiafei Zhang, Sheila M. Pimentel-Elardo, Andrew R. Johnson, Christiaan A. Rees, Stephanie E. Jones, Hindra, Sebastian S. Gehrke, Sonya Turvey, Suzanne Boursalie, Jane E. Hill, Erin E. Carlson, Justin R. Nodwell, Marie A. Elliot
bioRxiv 614727; doi: https://doi.org/10.1101/614727
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Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2
Emma J. Gehrke, Xiafei Zhang, Sheila M. Pimentel-Elardo, Andrew R. Johnson, Christiaan A. Rees, Stephanie E. Jones, Hindra, Sebastian S. Gehrke, Sonya Turvey, Suzanne Boursalie, Jane E. Hill, Erin E. Carlson, Justin R. Nodwell, Marie A. Elliot
bioRxiv 614727; doi: https://doi.org/10.1101/614727

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