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A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells

Wen Jin, Francesca Mulas, Bjoern Gaertner, Yinghui Sui, Jinzhao Wang, Chun Zeng, Nicholas Vinckier, Allen Wang, Kim-Vy Nguyen-Ngoc, Joshua Chiou, Klaus H. Kaestner, Kelly Frazer, Andrea C. Carrano, Hung-Ping Shih, Maike Sander
doi: https://doi.org/10.1101/618330
Wen Jin
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Francesca Mulas
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Bjoern Gaertner
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Yinghui Sui
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Jinzhao Wang
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Chun Zeng
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Nicholas Vinckier
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Allen Wang
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Kim-Vy Nguyen-Ngoc
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Joshua Chiou
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Klaus H. Kaestner
2Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA
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Kelly Frazer
3Department of Pediatrics, Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA
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Andrea C. Carrano
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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Hung-Ping Shih
4Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolic Research Institute, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
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Maike Sander
1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
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  • For correspondence: masander@ucsd.edu
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Article Information

doi 
https://doi.org/10.1101/618330
History 
  • April 25, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Wen Jin1,
  2. Francesca Mulas1,
  3. Bjoern Gaertner1,
  4. Yinghui Sui1,
  5. Jinzhao Wang1,
  6. Chun Zeng1,
  7. Nicholas Vinckier1,
  8. Allen Wang1,
  9. Kim-Vy Nguyen-Ngoc1,
  10. Joshua Chiou1,
  11. Klaus H. Kaestner2,
  12. Kelly Frazer3,
  13. Andrea C. Carrano1,
  14. Hung-Ping Shih4 and
  15. Maike Sander1,5,*
  1. 1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA 92093, USA
  2. 2Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA
  3. 3Department of Pediatrics, Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA
  4. 4Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolic Research Institute, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
  1. ↵*Correspondance: masander{at}ucsd.edu
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Posted April 25, 2019.
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A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells
Wen Jin, Francesca Mulas, Bjoern Gaertner, Yinghui Sui, Jinzhao Wang, Chun Zeng, Nicholas Vinckier, Allen Wang, Kim-Vy Nguyen-Ngoc, Joshua Chiou, Klaus H. Kaestner, Kelly Frazer, Andrea C. Carrano, Hung-Ping Shih, Maike Sander
bioRxiv 618330; doi: https://doi.org/10.1101/618330
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A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells
Wen Jin, Francesca Mulas, Bjoern Gaertner, Yinghui Sui, Jinzhao Wang, Chun Zeng, Nicholas Vinckier, Allen Wang, Kim-Vy Nguyen-Ngoc, Joshua Chiou, Klaus H. Kaestner, Kelly Frazer, Andrea C. Carrano, Hung-Ping Shih, Maike Sander
bioRxiv 618330; doi: https://doi.org/10.1101/618330

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