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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts ultimate human lifespan limit

View ORCID ProfileTimothy V. Pyrkov, Konstantin Avchaciov, View ORCID ProfileAndrei E. Tarkhov, Leonid I. Menshikov, Andrei V. Gudkov, View ORCID ProfilePeter O. Fedichev
doi: https://doi.org/10.1101/618876
Timothy V. Pyrkov
aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
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  • ORCID record for Timothy V. Pyrkov
  • For correspondence: tim.pyrkov@gero.com peter.fedichev@gero.com
Konstantin Avchaciov
aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
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Andrei E. Tarkhov
aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
bSkolkovo Institute of Science and Technology, Bolshoy Boulevard 30, bld. 1, Moscow 121205, Russia
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  • ORCID record for Andrei E. Tarkhov
Leonid I. Menshikov
aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
cNational Research Center “Kurchatov Institute”, 1, Akademika Kurchatova pl., Moscow 123182, Russia
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Andrei V. Gudkov
dRoswell Park Comprehensive Cancer Center, Elm and Carlton streets, Buffalo, NY 14263, USA
eGenome Protection, Inc. 640 Ellicott St #444, Buffalo, NY 14203, USA
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Peter O. Fedichev
aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
fMoscow Institute of Physics and Technology, 141700, Institutskii per. 9, Dolgoprudny, Moscow Region, Russia
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  • ORCID record for Peter O. Fedichev
  • For correspondence: tim.pyrkov@gero.com peter.fedichev@gero.com
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Article Information

doi 
https://doi.org/10.1101/618876
History 
  • August 3, 2020.

Article Versions

  • Version 1 (April 26, 2019 - 15:28).
  • Version 2 (July 26, 2019 - 17:19).
  • Version 3 (February 7, 2020 - 03:00).
  • You are viewing Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Timothy V. Pyrkova,*,
  2. Konstantin Avchaciova,
  3. Andrei E. Tarkhova,b,
  4. Leonid I. Menshikova,c,
  5. Andrei V. Gudkovd,e and
  6. Peter O. Fedicheva,f,*
  1. aGero LLC, 105064, Nizhny Susalny per. 5/4, Moscow, Russia
  2. bSkolkovo Institute of Science and Technology, Bolshoy Boulevard 30, bld. 1, Moscow 121205, Russia
  3. cNational Research Center “Kurchatov Institute”, 1, Akademika Kurchatova pl., Moscow 123182, Russia
  4. dRoswell Park Comprehensive Cancer Center, Elm and Carlton streets, Buffalo, NY 14263, USA
  5. eGenome Protection, Inc. 640 Ellicott St #444, Buffalo, NY 14203, USA
  6. fMoscow Institute of Physics and Technology, 141700, Institutskii per. 9, Dolgoprudny, Moscow Region, Russia
  1. ↵*To whom correspondence should be addressed. E-mail: tim.pyrkov{at}gero.com, peter.fedichev{at}gero.com
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Posted August 03, 2020.
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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts ultimate human lifespan limit
Timothy V. Pyrkov, Konstantin Avchaciov, Andrei E. Tarkhov, Leonid I. Menshikov, Andrei V. Gudkov, Peter O. Fedichev
bioRxiv 618876; doi: https://doi.org/10.1101/618876
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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts ultimate human lifespan limit
Timothy V. Pyrkov, Konstantin Avchaciov, Andrei E. Tarkhov, Leonid I. Menshikov, Andrei V. Gudkov, Peter O. Fedichev
bioRxiv 618876; doi: https://doi.org/10.1101/618876

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