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Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo
Andrew M. Taverner, Lu Yang, Zackery J. Barile, Becky Lin, Julie Peng, Ana Pinharanda, Arya Rao, Bartholomew P. Roland, Aaron D. Talsma, Daniel Wei, Georg Petschenka, Michael J. Palladino, View ORCID ProfilePeter Andolfatto
doi: https://doi.org/10.1101/621185
Andrew M. Taverner
1Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544
Lu Yang
2Dept. of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544
Zackery J. Barile
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Becky Lin
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Julie Peng
1Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544
Ana Pinharanda
5Department of Biological Sciences, Columbia University, New York, NY 10027
Arya Rao
5Department of Biological Sciences, Columbia University, New York, NY 10027
Bartholomew P. Roland
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Aaron D. Talsma
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Daniel Wei
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Georg Petschenka
6Institute for Insect Biotechnology, Justus-Liebig-Universität Gießen, Hesse, Germany
Michael J. Palladino
3Dept. of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261
4Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
Peter Andolfatto
5Department of Biological Sciences, Columbia University, New York, NY 10027
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Posted April 28, 2019.
Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo
Andrew M. Taverner, Lu Yang, Zackery J. Barile, Becky Lin, Julie Peng, Ana Pinharanda, Arya Rao, Bartholomew P. Roland, Aaron D. Talsma, Daniel Wei, Georg Petschenka, Michael J. Palladino, Peter Andolfatto
bioRxiv 621185; doi: https://doi.org/10.1101/621185
Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo
Andrew M. Taverner, Lu Yang, Zackery J. Barile, Becky Lin, Julie Peng, Ana Pinharanda, Arya Rao, Bartholomew P. Roland, Aaron D. Talsma, Daniel Wei, Georg Petschenka, Michael J. Palladino, Peter Andolfatto
bioRxiv 621185; doi: https://doi.org/10.1101/621185
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