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Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences

Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, Rob Fergus
doi: https://doi.org/10.1101/622803
Alexander Rives
1Facebook AI Research
2Dept. of Computer Science, New York University
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  • For correspondence: arives@cs.nyu.edu
Joshua Meier
1Facebook AI Research
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Tom Sercu
1Facebook AI Research
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Siddharth Goyal
1Facebook AI Research
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Zeming Lin
2Dept. of Computer Science, New York University
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Jason Liu
1Facebook AI Research
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Demi Guo
3Harvard University
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Myle Ott
1Facebook AI Research
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C. Lawrence Zitnick
1Facebook AI Research
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Jerry Ma
4Booth School of Business, University of Chicago & Yale Law School
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Rob Fergus
2Dept. of Computer Science, New York University
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Article Information

doi 
https://doi.org/10.1101/622803
History 
  • December 15, 2020.

Article Versions

  • Version 1 (April 29, 2019 - 20:19).
  • Version 2 (May 29, 2019 - 18:01).
  • Version 3 (August 31, 2020 - 18:28).
  • You are viewing Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Alexander Rives*,1,2,+,
  2. Joshua Meier*,1,
  3. Tom Sercu*,1,
  4. Siddharth Goyal*,1,
  5. Zeming Lin2,
  6. Jason Liu1,
  7. Demi Guo3,†,
  8. Myle Ott1,
  9. C. Lawrence Zitnick1,
  10. Jerry Ma4,† and
  11. Rob Fergus2
  1. 1Facebook AI Research
  2. 2Dept. of Computer Science, New York University
  3. 3Harvard University
  4. 4Booth School of Business, University of Chicago & Yale Law School
  1. ↵+Correspondence to: Alexander Rives <arives{at}cs.nyu.edu>. Pre-trained models available at: <https://github.com/facebookresearch/esm>.
  1. ↵* Equal contribution

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Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, Rob Fergus
bioRxiv 622803; doi: https://doi.org/10.1101/622803
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Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
Alexander Rives, Joshua Meier, Tom Sercu, Siddharth Goyal, Zeming Lin, Jason Liu, Demi Guo, Myle Ott, C. Lawrence Zitnick, Jerry Ma, Rob Fergus
bioRxiv 622803; doi: https://doi.org/10.1101/622803

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