New Results
Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion
Jiyeon Choi, Tongwu Zhang, Andrew Vu, Julien Ablain, Matthew M Makowski, Leandro M Colli, Mai Xu, Harriet Rothschild, Cathrin Gräwe, Michael A Kovacs, Myriam Brossard, John Taylor, Bogdan Pasaniuc, Raj Chari, Stephen J Chanock, Clive J Hoggart, Florence Demenais, Jennifer H Barrett, Matthew H Law, Mark M Iles, Kai Yu, Michiel Vermeulen, Leonard I Zon, Kevin M Brown
doi: https://doi.org/10.1101/625400
Jiyeon Choi
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Tongwu Zhang
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Andrew Vu
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Julien Ablain
2Stem Cell Program and Division of Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, MA, 02115, USA
Matthew M Makowski
3Department of Molecular Biology, Oncode Institute, Radboud University, Nijmegen, Netherlands
Leandro M Colli
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Mai Xu
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Harriet Rothschild
2Stem Cell Program and Division of Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, MA, 02115, USA
Cathrin Gräwe
3Department of Molecular Biology, Oncode Institute, Radboud University, Nijmegen, Netherlands
Michael A Kovacs
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Myriam Brossard
4Genetic Variation and Human Diseases Unit, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot, Paris, France
John Taylor
5Leeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds, UK
Bogdan Pasaniuc
6Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90024, USA
Raj Chari
7Genome Modification Core, Frederick National Lab for Cancer Research, National Cancer Institute, Frederick, MD, 21701, USA
Stephen J Chanock
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Clive J Hoggart
8Department of Medicine, Imperial College London, London, UK
Florence Demenais
4Genetic Variation and Human Diseases Unit, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot, Paris, France
Jennifer H Barrett
5Leeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds, UK
Matthew H Law
9Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Mark M Iles
5Leeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds, UK
Kai Yu
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Michiel Vermeulen
3Department of Molecular Biology, Oncode Institute, Radboud University, Nijmegen, Netherlands
Leonard I Zon
2Stem Cell Program and Division of Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, MA, 02115, USA
Kevin M Brown
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA
Posted May 02, 2019.
Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion
Jiyeon Choi, Tongwu Zhang, Andrew Vu, Julien Ablain, Matthew M Makowski, Leandro M Colli, Mai Xu, Harriet Rothschild, Cathrin Gräwe, Michael A Kovacs, Myriam Brossard, John Taylor, Bogdan Pasaniuc, Raj Chari, Stephen J Chanock, Clive J Hoggart, Florence Demenais, Jennifer H Barrett, Matthew H Law, Mark M Iles, Kai Yu, Michiel Vermeulen, Leonard I Zon, Kevin M Brown
bioRxiv 625400; doi: https://doi.org/10.1101/625400
Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion
Jiyeon Choi, Tongwu Zhang, Andrew Vu, Julien Ablain, Matthew M Makowski, Leandro M Colli, Mai Xu, Harriet Rothschild, Cathrin Gräwe, Michael A Kovacs, Myriam Brossard, John Taylor, Bogdan Pasaniuc, Raj Chari, Stephen J Chanock, Clive J Hoggart, Florence Demenais, Jennifer H Barrett, Matthew H Law, Mark M Iles, Kai Yu, Michiel Vermeulen, Leonard I Zon, Kevin M Brown
bioRxiv 625400; doi: https://doi.org/10.1101/625400
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