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Stochastic modeling of aging cells reveals how damage accumulation, repair, and cell-division asymmetry affect clonal senescence and population fitness
Ruijie Song, Murat Acar
doi: https://doi.org/10.1101/628669
Ruijie Song
1Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT 06516
2Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, Suite 501, New Haven, CT 06511
Murat Acar
1Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT 06516
2Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, Suite 501, New Haven, CT 06511
3Department of Molecular Cellular and Developmental Biology, Yale University, 219 Prospect Street, New Haven, CT 06511
4Department of Physics, Yale University, 217 Prospect Street, New Haven, CT 06511
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Posted May 05, 2019.
Stochastic modeling of aging cells reveals how damage accumulation, repair, and cell-division asymmetry affect clonal senescence and population fitness
Ruijie Song, Murat Acar
bioRxiv 628669; doi: https://doi.org/10.1101/628669
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