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The plastidial exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of N-hydroxy pipecolic acid

Dmitrij Rekhter, Lennart Mohnike, Kirstin Feussner, Krzysztof Zienkiewicz, Yuelin Zhang, Ivo Feussner
doi: https://doi.org/10.1101/630723
Dmitrij Rekhter
1University of Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, D-37077 Goettingen, Germany
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Lennart Mohnike
1University of Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, D-37077 Goettingen, Germany
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Kirstin Feussner
1University of Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, D-37077 Goettingen, Germany
2University of Goettingen, Goettingen Center for Molecular Biosciences (GZMB), Service Unit for Metabolomics and Lipidomics, D-37077 Goettingen, Germany
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Krzysztof Zienkiewicz
1University of Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, D-37077 Goettingen, Germany
2University of Goettingen, Goettingen Center for Molecular Biosciences (GZMB), Service Unit for Metabolomics and Lipidomics, D-37077 Goettingen, Germany
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Yuelin Zhang
3University of British Columbia, Department of Botany, Vancouver, BC V6T 1Z4, Canada
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Ivo Feussner
1University of Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Department of Plant Biochemistry, D-37077 Goettingen, Germany
2University of Goettingen, Goettingen Center for Molecular Biosciences (GZMB), Service Unit for Metabolomics and Lipidomics, D-37077 Goettingen, Germany
4University of Goettingen, Goettingen Center for Molecular Biosciences (GZMB), Department of Plant Biochemistry, D-37077 Goettingen, Germany
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  • For correspondence: ifeussn@uni-goettingen.de
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Abstract

Pipecolic acid is essential for the establishment of systemic acquired resistance in plants. It is synthesized in the plastid and further processed in the cytosol to its active form N-hydroxy pipecolic acid. Here we provide strong evidence that the exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of not only salicylic acid, but also N-hydroxy pipecolic acid, suggesting that it represents a convergent point of plant immunity.

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Posted May 29, 2019.
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The plastidial exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of N-hydroxy pipecolic acid
Dmitrij Rekhter, Lennart Mohnike, Kirstin Feussner, Krzysztof Zienkiewicz, Yuelin Zhang, Ivo Feussner
bioRxiv 630723; doi: https://doi.org/10.1101/630723
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The plastidial exporter Enhanced Disease Susceptibility 5 is required for the biosynthesis of N-hydroxy pipecolic acid
Dmitrij Rekhter, Lennart Mohnike, Kirstin Feussner, Krzysztof Zienkiewicz, Yuelin Zhang, Ivo Feussner
bioRxiv 630723; doi: https://doi.org/10.1101/630723

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