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Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Linara G. Cornell, Suraj Peri, Diana Restifo, Alena Klochkova, Tiffiney R. Hartman, Alana M. O’Reilly, Ralph Francescone, Janusz Franco-Barraza, Neelima Shah, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Alexandra Mazitova, Ido Sloma, Rachel Chiaverelli, Richard Moffitt, Erica A. Golemis, Edna Cukierman, View ORCID ProfileIgor Astsaturov
doi: https://doi.org/10.1101/633719
Linara G. Cornell
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Suraj Peri
3Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Diana Restifo
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Alena Klochkova
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Tiffiney R. Hartman
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Alana M. O’Reilly
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Ralph Francescone
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
4Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Janusz Franco-Barraza
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
4Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Neelima Shah
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
4Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Emmanuelle Nicolas
4Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Elizabeth A. Handorf
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Kathy Q. Cai
5Histopathology Facility, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Alexandra Mazitova
6Kazan Federal University, Kazan, Russian Federation
Ido Sloma
7Champions Oncology Inc., Hackensack, NJ
Rachel Chiaverelli
7Champions Oncology Inc., Hackensack, NJ
Richard Moffitt
8Department of Biomedical Informatics, Stony Brook Cancer Center, Stony Brook, NY
Erica A. Golemis
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Edna Cukierman
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
4Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Igor Astsaturov
1Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
2The Marvin & Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA
Article usage
Posted May 11, 2019.
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Linara G. Cornell, Suraj Peri, Diana Restifo, Alena Klochkova, Tiffiney R. Hartman, Alana M. O’Reilly, Ralph Francescone, Janusz Franco-Barraza, Neelima Shah, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Alexandra Mazitova, Ido Sloma, Rachel Chiaverelli, Richard Moffitt, Erica A. Golemis, Edna Cukierman, Igor Astsaturov
bioRxiv 633719; doi: https://doi.org/10.1101/633719
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Linara G. Cornell, Suraj Peri, Diana Restifo, Alena Klochkova, Tiffiney R. Hartman, Alana M. O’Reilly, Ralph Francescone, Janusz Franco-Barraza, Neelima Shah, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Alexandra Mazitova, Ido Sloma, Rachel Chiaverelli, Richard Moffitt, Erica A. Golemis, Edna Cukierman, Igor Astsaturov
bioRxiv 633719; doi: https://doi.org/10.1101/633719
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