Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

Brian Arnold; Mashaal Sohail; Crista Wadsworth; Jukka Corander; William P. Hanage; Shamil Sunyaev; Yonatan H. Grad

doi:10.1101/634147

New Results

Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

Brian Arnold, Mashaal Sohail, Crista Wadsworth, Jukka Corander, William P. Hanage, Shamil Sunyaev, Yonatan H. Grad

doi: https://doi.org/10.1101/634147

Brian Arnold

1Division of Informatics, Faculty of Arts and Sciences, Harvard University, Cambridge, MA 02138, USA

2Center for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: brianjohnarnold@gmail.com

Mashaal Sohail

3Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA

4Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Crista Wadsworth

5Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jukka Corander

6Department of Biostatistics, University of Oslo, Postboks 1122, Blindern, 0317 Oslo, Norway

7Helsinki Institute for Information Technology HIIT, Department of Computer Science, University of Helsinki, Helsinki, Finland

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

William P. Hanage

2Center for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shamil Sunyaev

3Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA

4Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yonatan H. Grad

5Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA

8Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

TableS1[supplements/634147_file03.xlsx]
TableS2[supplements/634147_file04.xlsx]
TableS3[supplements/634147_file05.xlsx]
TableS4[supplements/634147_file06.xlsx]
TableS5[supplements/634147_file07.xlsx]
Supplementary Material[supplements/634147_file08.pdf]

View the discussion thread.

PreviousNext

Posted May 10, 2019.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

Brian Arnold, Mashaal Sohail, Crista Wadsworth, Jukka Corander, William P. Hanage, Shamil Sunyaev, Yonatan H. Grad

bioRxiv 634147; doi: https://doi.org/10.1101/634147

Share This Article:

Citation Tools

Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

Brian Arnold, Mashaal Sohail, Crista Wadsworth, Jukka Corander, William P. Hanage, Shamil Sunyaev, Yonatan H. Grad

bioRxiv 634147; doi: https://doi.org/10.1101/634147

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Evolutionary Biology

Subject Areas

All Articles

Animal Behavior and Cognition (4863)
Biochemistry (10820)
Bioengineering (8061)
Bioinformatics (27368)
Biophysics (14012)
Cancer Biology (11155)
Cell Biology (16091)
Clinical Trials (138)
Developmental Biology (8806)
Ecology (13321)
Epidemiology (2067)
Evolutionary Biology (17387)
Genetics (11702)
Genomics (15955)
Immunology (11055)
Microbiology (26147)
Molecular Biology (10673)
Neuroscience (56691)
Paleontology (422)
Pathology (1737)
Pharmacology and Toxicology (3012)
Physiology (4564)
Plant Biology (9662)
Scientific Communication and Education (1617)
Synthetic Biology (2697)
Systems Biology (6991)
Zoology (1513)