New Results
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads
View ORCID ProfileMitchell R. Vollger, View ORCID ProfileGlennis A. Logsdon, View ORCID ProfilePeter A. Audano, View ORCID ProfileArvis Sulovari, David Porubsky, Paul Peluso, Gregory T. Concepcion, View ORCID ProfileKatherine M. Munson, Carl Baker, Ashley D. Sanders, View ORCID ProfileDiana C.J. Spierings, View ORCID ProfilePeter M. Lansdorp, Michael W. Hunkapiller, View ORCID ProfileEvan E. Eichler
doi: https://doi.org/10.1101/635037
Mitchell R. Vollger
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Glennis A. Logsdon
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Peter A. Audano
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Arvis Sulovari
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
David Porubsky
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Paul Peluso
2Pacific Biosciences of California, Inc., Menlo Park, CA 94025, USA
Gregory T. Concepcion
2Pacific Biosciences of California, Inc., Menlo Park, CA 94025, USA
Katherine M. Munson
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Carl Baker
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Ashley D. Sanders
3European Molecular Biology Laboratory, Genome Biology Unit, 69117, Heidelberg, Germany
Diana C.J. Spierings
4European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands
Peter M. Lansdorp
4European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands
5Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada
6Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Michael W. Hunkapiller
2Pacific Biosciences of California, Inc., Menlo Park, CA 94025, USA
Evan E. Eichler
1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
7Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
Article usage
Posted May 10, 2019.
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads
Mitchell R. Vollger, Glennis A. Logsdon, Peter A. Audano, Arvis Sulovari, David Porubsky, Paul Peluso, Gregory T. Concepcion, Katherine M. Munson, Carl Baker, Ashley D. Sanders, Diana C.J. Spierings, Peter M. Lansdorp, Michael W. Hunkapiller, Evan E. Eichler
bioRxiv 635037; doi: https://doi.org/10.1101/635037
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads
Mitchell R. Vollger, Glennis A. Logsdon, Peter A. Audano, Arvis Sulovari, David Porubsky, Paul Peluso, Gregory T. Concepcion, Katherine M. Munson, Carl Baker, Ashley D. Sanders, Diana C.J. Spierings, Peter M. Lansdorp, Michael W. Hunkapiller, Evan E. Eichler
bioRxiv 635037; doi: https://doi.org/10.1101/635037
Subject Area
Subject Areas
- Biochemistry (11755)
- Bioengineering (8757)
- Bioinformatics (29209)
- Biophysics (14980)
- Cancer Biology (12103)
- Cell Biology (17416)
- Clinical Trials (138)
- Developmental Biology (9425)
- Ecology (14187)
- Epidemiology (2067)
- Evolutionary Biology (18314)
- Genetics (12246)
- Genomics (16807)
- Immunology (11870)
- Microbiology (28101)
- Molecular Biology (11599)
- Neuroscience (60995)
- Paleontology (452)
- Pathology (1872)
- Pharmacology and Toxicology (3238)
- Physiology (4961)
- Plant Biology (10429)
- Synthetic Biology (2887)
- Systems Biology (7341)
- Zoology (1651)