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De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits
Simon Ng, Yu-Chi Juang, Arun Chandramohan, Hung Yi Kristal Kaan, Ahmad Sadruddin, Tsz Ying Yuen, Fernando J. Ferrer, Xue’Er Cheryl Lee, Liew Xi, Charles W. Johannes, Christopher J. Brown, Srinivasaraghavan Kannan, Pietro G. Aronica, Nils Berglund, Chandra S. Verma, Lijuan Liu, Alexander Stoeck, Tomi K. Sawyer, Anthony W. Partridge, David P. Lane
doi: https://doi.org/10.1101/636563
Simon Ng
ap53 Laboratory, A*STAR, Singapore
Yu-Chi Juang
bMSD, Singapore
Arun Chandramohan
bMSD, Singapore
Hung Yi Kristal Kaan
bMSD, Singapore
Ahmad Sadruddin
bMSD, Singapore
Tsz Ying Yuen
cInstitute of Chemical and Engineering Sciences, A*STAR, Singapore
Fernando J. Ferrer
ap53 Laboratory, A*STAR, Singapore
Xue’Er Cheryl Lee
cInstitute of Chemical and Engineering Sciences, A*STAR, Singapore
Liew Xi
cInstitute of Chemical and Engineering Sciences, A*STAR, Singapore
Charles W. Johannes
cInstitute of Chemical and Engineering Sciences, A*STAR, Singapore
Christopher J. Brown
ap53 Laboratory, A*STAR, Singapore
Srinivasaraghavan Kannan
dBioinformatics Institute, A*STAR, Singapore
Pietro G. Aronica
dBioinformatics Institute, A*STAR, Singapore
Nils Berglund
dBioinformatics Institute, A*STAR, Singapore
Chandra S. Verma
dBioinformatics Institute, A*STAR, Singapore
Lijuan Liu
eMerck & Co., Inc., Boston, MA, USA
Alexander Stoeck
eMerck & Co., Inc., Boston, MA, USA
Tomi K. Sawyer
eMerck & Co., Inc., Boston, MA, USA
Anthony W. Partridge
bMSD, Singapore
David P. Lane
ap53 Laboratory, A*STAR, Singapore
Article usage
Posted May 15, 2019.
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits
Simon Ng, Yu-Chi Juang, Arun Chandramohan, Hung Yi Kristal Kaan, Ahmad Sadruddin, Tsz Ying Yuen, Fernando J. Ferrer, Xue’Er Cheryl Lee, Liew Xi, Charles W. Johannes, Christopher J. Brown, Srinivasaraghavan Kannan, Pietro G. Aronica, Nils Berglund, Chandra S. Verma, Lijuan Liu, Alexander Stoeck, Tomi K. Sawyer, Anthony W. Partridge, David P. Lane
bioRxiv 636563; doi: https://doi.org/10.1101/636563
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits
Simon Ng, Yu-Chi Juang, Arun Chandramohan, Hung Yi Kristal Kaan, Ahmad Sadruddin, Tsz Ying Yuen, Fernando J. Ferrer, Xue’Er Cheryl Lee, Liew Xi, Charles W. Johannes, Christopher J. Brown, Srinivasaraghavan Kannan, Pietro G. Aronica, Nils Berglund, Chandra S. Verma, Lijuan Liu, Alexander Stoeck, Tomi K. Sawyer, Anthony W. Partridge, David P. Lane
bioRxiv 636563; doi: https://doi.org/10.1101/636563
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