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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis Jr., So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Reuben Shaw, Andrew Sproul, View ORCID ProfileFranck Polleux
doi: https://doi.org/10.1101/637199
Annie Lee
1Department of Neuroscience, Columbia University Medical Center New York, NY
2Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY
4The Integrated Graduate Program in Cellular, Molecular, and Biomedical Studies, Columbia University Medical Center, New York, NY
Chandana Kondapalli
1Department of Neuroscience, Columbia University Medical Center New York, NY
2Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY
Daniel M. Virga
1Department of Neuroscience, Columbia University Medical Center New York, NY
2Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY
6Department of Biological Sciences, Columbia University, New York, NY
Tommy L. Lewis Jr.
1Department of Neuroscience, Columbia University Medical Center New York, NY
2Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY
So Yeon Koo
5Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY
7Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, NY
Archana Ashok
5Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY
7Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, NY
Georges Mairet-Coello
8UCB Biopharma, Braine l’Alleud, Belgium
Sebastien Herzig
9Molecular and Cell Biology Laboratory-Salk Institute for Biological Studies, La Jolla, CA 92037, USA
Reuben Shaw
9Molecular and Cell Biology Laboratory-Salk Institute for Biological Studies, La Jolla, CA 92037, USA
Andrew Sproul
5Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY
7Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, NY
Franck Polleux
1Department of Neuroscience, Columbia University Medical Center New York, NY
2Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY
3Kavli Institute for Brain Sciences, Columbia University Medical Center, New York, NY
Article usage
Posted May 14, 2019.
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis Jr., So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Reuben Shaw, Andrew Sproul, Franck Polleux
bioRxiv 637199; doi: https://doi.org/10.1101/637199
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis Jr., So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Reuben Shaw, Andrew Sproul, Franck Polleux
bioRxiv 637199; doi: https://doi.org/10.1101/637199
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