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A low-cost and high-precision scanning electrochemical microscope built with open source tools

Alperen Guver, Nafetalai Fifita, Peker Milas, Michael Straker, Michael Guy, Kara Green, Taha Yildirim, Ilyas Unlu, Veysel Yigit, View ORCID ProfileBirol Ozturk
doi: https://doi.org/10.1101/645283
Alperen Guver
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Nafetalai Fifita
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Peker Milas
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Michael Straker
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Michael Guy
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Kara Green
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Taha Yildirim
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Ilyas Unlu
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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Veysel Yigit
2Department of Chemistry and the RNA Institute, University at Albany, State University of New York, Albany, New York, United States of America
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Birol Ozturk
1Department of Physics and Engineering Physics, Morgan State University, Baltimore, Maryland, United States of America
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  • ORCID record for Birol Ozturk
  • For correspondence: birol.ozturk@morgan.edu
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Abstract

A low-cost Scanning Electrochemical Microscope (SECM) was built with a 0.6 pA current measurement capability potentiostat and submicron resolution motorized stage, using open source software and hardware tools. The high performance potentiostat with a Python graphical user interface was built based on an open source project. Arduino boards, stepper motors, a manual XY micromanipulator stage, 3D printed couplers and gears were used in building the motorized stage. An open source motor control software was used for moving the motorized stage with high precision. An inverted microscope was utilized for viewing a standard microelectrode while scanning. The setup was tested in the formation of a map of electrochemical signals from an array of pores on a parafilm membrane. As the setup will be used in future biosensing experiments, DNA hybridization detection experiments were also performed with the setup.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
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Posted May 21, 2019.
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A low-cost and high-precision scanning electrochemical microscope built with open source tools
Alperen Guver, Nafetalai Fifita, Peker Milas, Michael Straker, Michael Guy, Kara Green, Taha Yildirim, Ilyas Unlu, Veysel Yigit, Birol Ozturk
bioRxiv 645283; doi: https://doi.org/10.1101/645283
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A low-cost and high-precision scanning electrochemical microscope built with open source tools
Alperen Guver, Nafetalai Fifita, Peker Milas, Michael Straker, Michael Guy, Kara Green, Taha Yildirim, Ilyas Unlu, Veysel Yigit, Birol Ozturk
bioRxiv 645283; doi: https://doi.org/10.1101/645283

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