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Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma
View ORCID ProfileTakashi Sato, Seungyeul Yoo, Ranran Kong, Maya Fridrikh, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe
doi: https://doi.org/10.1101/646034
Takashi Sato
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Seungyeul Yoo
3Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Ranran Kong
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
4Department of Thoracic Surgery, The Second Affiliated Hospital of Medical School, Xi’an Jiaotong University, Xi’an, Shaanxi 710004, China
Maya Fridrikh
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Abhilasha Sinha
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Prashanth Chandramani-Shivalingappa
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Ayushi Patel
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Osamu Nagano
5Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan
Takashi Masuko
6Cell Biology Laboratory, School of Pharmacy, Kindai University, Higashiosaka, Osaka 577-8502, Japan
Mary Beth Beasley
7Department of Pathology and Laboratory Medicine, Icahn School of Medicine at Mount Sinai, NY 10029, USA
Charles A. Powell
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Jun Zhu
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
3Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
8Sema4, a Mount Sinai venture, Stamford, CT 06902, USA
Hideo Watanabe
1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
3Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
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Posted June 12, 2019.
Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma
Takashi Sato, Seungyeul Yoo, Ranran Kong, Maya Fridrikh, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe
bioRxiv 646034; doi: https://doi.org/10.1101/646034
Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma
Takashi Sato, Seungyeul Yoo, Ranran Kong, Maya Fridrikh, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe
bioRxiv 646034; doi: https://doi.org/10.1101/646034
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