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Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus
View ORCID ProfileStephanie M. Reeve, Debjani Si, Jolanta Krucinska, Yongzhao Yan, Kishore Viswanathan, Siyu Wang, Graham T. Holt, Marcel S. Frenkel, Adegoke A. Ojewole, Alexavier Estrada, Sherry S. Agabiti, Jeremy B. Alverson, Nathan D. Gibson, Nigel D. Priestly, Andrew J. Wiemer, Bruce R. Donald, Dennis L. Wright
doi: https://doi.org/10.1101/648808
Stephanie M. Reeve
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Debjani Si
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Jolanta Krucinska
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Yongzhao Yan
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Kishore Viswanathan
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Siyu Wang
2Department of Computer Science, Duke University, Durham, NC 27708 USA
3Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708 USA
Graham T. Holt
4Department of Biochemistry, Duke University Medical Center, Durham, NC 27710 USA
Marcel S. Frenkel
4Department of Biochemistry, Duke University Medical Center, Durham, NC 27710 USA
Adegoke A. Ojewole
2Department of Computer Science, Duke University, Durham, NC 27708 USA
3Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708 USA
Alexavier Estrada
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Sherry S. Agabiti
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Jeremy B. Alverson
5Department of Chemistry, University of Montana, Missoula, MT 59812, USA
Nathan D. Gibson
5Department of Chemistry, University of Montana, Missoula, MT 59812, USA
Nigel D. Priestly
5Department of Chemistry, University of Montana, Missoula, MT 59812, USA
Andrew J. Wiemer
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
Bruce R. Donald
2Department of Computer Science, Duke University, Durham, NC 27708 USA
4Department of Biochemistry, Duke University Medical Center, Durham, NC 27710 USA
6Department of Chemistry, Duke University, Durham, NC 27708 USA
Dennis L. Wright
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269 USA
7Department of Chemistry, University of Connecticut, Storrs, CT 06269 USA
Article usage
Posted May 24, 2019.
Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus
Stephanie M. Reeve, Debjani Si, Jolanta Krucinska, Yongzhao Yan, Kishore Viswanathan, Siyu Wang, Graham T. Holt, Marcel S. Frenkel, Adegoke A. Ojewole, Alexavier Estrada, Sherry S. Agabiti, Jeremy B. Alverson, Nathan D. Gibson, Nigel D. Priestly, Andrew J. Wiemer, Bruce R. Donald, Dennis L. Wright
bioRxiv 648808; doi: https://doi.org/10.1101/648808
Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus
Stephanie M. Reeve, Debjani Si, Jolanta Krucinska, Yongzhao Yan, Kishore Viswanathan, Siyu Wang, Graham T. Holt, Marcel S. Frenkel, Adegoke A. Ojewole, Alexavier Estrada, Sherry S. Agabiti, Jeremy B. Alverson, Nathan D. Gibson, Nigel D. Priestly, Andrew J. Wiemer, Bruce R. Donald, Dennis L. Wright
bioRxiv 648808; doi: https://doi.org/10.1101/648808
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