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Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes
View ORCID ProfileAna Viñuela, View ORCID ProfileArushi Varshney, View ORCID ProfileMartijn van de Bunt, View ORCID ProfileRashmi B. Prasad, Olof Asplund, Amanda Bennett, View ORCID ProfileMichael Boehnke, View ORCID ProfileAndrew Brown, View ORCID ProfileMichael R. Erdos, João Fadista, View ORCID ProfileOla Hansson, Gad Hatem, Cédric Howald, Apoorva K. Iyengar, Paul Johnson, Ulrika Krus, View ORCID ProfilePatrick E. MacDonald, View ORCID ProfileAnubha Mahajan, Jocelyn E. Manning Fox, View ORCID ProfileNarisu Narisu, View ORCID ProfileVibe Nylander, View ORCID ProfilePeter Orchard, Nikolay Oskolkov, View ORCID ProfileNikolaos I. Panousis, Anthony Payne, View ORCID ProfileMichael L. Stitzel, Swarooparani Vadlamudi, View ORCID ProfileRyan Welch, View ORCID ProfileFrancis S. Collins, View ORCID ProfileKaren L. Mohlke, View ORCID ProfileAnna L. Gloyn, View ORCID ProfileLaura J. Scott, View ORCID ProfileEmmanouil T. Dermitzakis, Leif Groop, View ORCID ProfileStephen C.J. Parker, View ORCID ProfileMark I. McCarthy
doi: https://doi.org/10.1101/655670
Ana Viñuela
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, SwitzerlandInstitute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, SwitzerlandSwiss Institute of Bioinformatics, 1211 Geneva, Switzerland
Arushi Varshney
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109
Martijn van de Bunt
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UKOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UKOxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, OX3 7LE, UK
Rashmi B. Prasad
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Olof Asplund
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Amanda Bennett
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK
Michael Boehnke
Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109
Andrew Brown
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, SwitzerlandInstitute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, SwitzerlandSwiss Institute of Bioinformatics, 1211 Geneva, Switzerland
Michael R. Erdos
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA
João Fadista
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, SwedenDepartment of Genetics, University of North Carolina, Chapel Hill, NC 27599
Ola Hansson
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Gad Hatem
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Cédric Howald
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, SwitzerlandInstitute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, SwitzerlandSwiss Institute of Bioinformatics, 1211 Geneva, Switzerland
Apoorva K. Iyengar
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599
Paul Johnson
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK
Ulrika Krus
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Patrick E. MacDonald
Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Anubha Mahajan
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK
Jocelyn E. Manning Fox
Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Narisu Narisu
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA
Vibe Nylander
Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK
Peter Orchard
Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109
Nikolay Oskolkov
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden
Nikolaos I. Panousis
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, SwitzerlandInstitute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, SwitzerlandSwiss Institute of Bioinformatics, 1211 Geneva, Switzerland
Anthony Payne
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK
Michael L. Stitzel
The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032Department of Genetics and Genome Sciences, Institute for Systems Genomics, University of Connecticut, Farmington, CT 06032
Swarooparani Vadlamudi
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599
Ryan Welch
Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109
Francis S. Collins
Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA
Karen L. Mohlke
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599
Anna L. Gloyn
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UKOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UKOxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, OX3 7LE, UK
Laura J. Scott
Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109
Emmanouil T. Dermitzakis
Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, SwitzerlandInstitute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211 Geneva, SwitzerlandSwiss Institute of Bioinformatics, 1211 Geneva, Switzerland
Leif Groop
Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, SwedenFinnish Institute for Molecular Medicine (FIMM), University of Helsinki, Helsinki, Finland
Stephen C.J. Parker
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109
Mark I. McCarthy
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UKOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UKOxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, OX3 7LE, UK
Article usage
Posted May 31, 2019.
Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes
Ana Viñuela, Arushi Varshney, Martijn van de Bunt, Rashmi B. Prasad, Olof Asplund, Amanda Bennett, Michael Boehnke, Andrew Brown, Michael R. Erdos, João Fadista, Ola Hansson, Gad Hatem, Cédric Howald, Apoorva K. Iyengar, Paul Johnson, Ulrika Krus, Patrick E. MacDonald, Anubha Mahajan, Jocelyn E. Manning Fox, Narisu Narisu, Vibe Nylander, Peter Orchard, Nikolay Oskolkov, Nikolaos I. Panousis, Anthony Payne, Michael L. Stitzel, Swarooparani Vadlamudi, Ryan Welch, Francis S. Collins, Karen L. Mohlke, Anna L. Gloyn, Laura J. Scott, Emmanouil T. Dermitzakis, Leif Groop, Stephen C.J. Parker, Mark I. McCarthy
bioRxiv 655670; doi: https://doi.org/10.1101/655670
Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes
Ana Viñuela, Arushi Varshney, Martijn van de Bunt, Rashmi B. Prasad, Olof Asplund, Amanda Bennett, Michael Boehnke, Andrew Brown, Michael R. Erdos, João Fadista, Ola Hansson, Gad Hatem, Cédric Howald, Apoorva K. Iyengar, Paul Johnson, Ulrika Krus, Patrick E. MacDonald, Anubha Mahajan, Jocelyn E. Manning Fox, Narisu Narisu, Vibe Nylander, Peter Orchard, Nikolay Oskolkov, Nikolaos I. Panousis, Anthony Payne, Michael L. Stitzel, Swarooparani Vadlamudi, Ryan Welch, Francis S. Collins, Karen L. Mohlke, Anna L. Gloyn, Laura J. Scott, Emmanouil T. Dermitzakis, Leif Groop, Stephen C.J. Parker, Mark I. McCarthy
bioRxiv 655670; doi: https://doi.org/10.1101/655670
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