Genetics of 38 blood and urine biomarkers in the UK Biobank

Nasa Sinnott-Armstrong; Yosuke Tanigawa; David Amar; Nina J. Mars; Matthew Aguirre; Guhan Ram Venkataraman; Michael Wainberg; Hanna M. Ollila; James P. Pirruccello; Junyang Qian; Anna Shcherbina; FinnGen; Fatima Rodriguez; Themistocles L. Assimes; Vineeta Agarwala; Robert Tibshirani; Trevor Hastie; Samuli Ripatti; Jonathan K. Pritchard; Mark J. Daly; Manuel A. Rivas

doi:10.1101/660506

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Genetics of 38 blood and urine biomarkers in the UK Biobank

View ORCID ProfileNasa Sinnott-Armstrong, View ORCID ProfileYosuke Tanigawa, View ORCID ProfileDavid Amar, View ORCID ProfileNina J. Mars, View ORCID ProfileMatthew Aguirre, View ORCID ProfileGuhan Ram Venkataraman, Michael Wainberg, Hanna M. Ollila, James P. Pirruccello, Junyang Qian, View ORCID ProfileAnna Shcherbina, FinnGen, Fatima Rodriguez, View ORCID ProfileThemistocles L. Assimes, Vineeta Agarwala, Robert Tibshirani, Trevor Hastie, Samuli Ripatti, View ORCID ProfileJonathan K. Pritchard, View ORCID ProfileMark J. Daly, View ORCID ProfileManuel A. Rivas

doi: https://doi.org/10.1101/660506

Nasa Sinnott-Armstrong

1Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA

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For correspondence: mrivas@stanford.edu nasa@stanford.edu

Yosuke Tanigawa

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

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David Amar

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

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Nina J. Mars

3Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

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Matthew Aguirre

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

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Guhan Ram Venkataraman

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

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Michael Wainberg

4Department of Computer Science, Stanford University, Stanford, CA, USA

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Hanna M. Ollila

3Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

5Stanford University, Department of Psychiatry and Behavioral Sciences, Palo Alto, CA, USA

6Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

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James P. Pirruccello

7Massachusetts General Hospital Division of Cardiology, Boston, MA, USA

8Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA

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Junyang Qian

9Department of Statistics, Stanford University, Stanford, CA, USA

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Anna Shcherbina

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

10Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA

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Fatima Rodriguez

10Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA

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Themistocles L. Assimes

10Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA

11VA Palo Alto Health Care System, Palo Alto, CA, USA

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Vineeta Agarwala

10Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA

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Robert Tibshirani

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

9Department of Statistics, Stanford University, Stanford, CA, USA

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Trevor Hastie

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

9Department of Statistics, Stanford University, Stanford, CA, USA

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Samuli Ripatti

3Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

8Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA

12Department of Public Health, Clinicum, University of Helsinki, Helsinki, Finland

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Jonathan K. Pritchard

1Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA

13Department of Biology, Stanford University, Stanford, CA, USA

14Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA

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Mark J. Daly

3Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

8Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA

15Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA., USA

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Manuel A. Rivas

2Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, CA, USA

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For correspondence: mrivas@stanford.edu nasa@stanford.edu

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Genetics of 38 blood and urine biomarkers in the UK Biobank

Nasa Sinnott-Armstrong, Yosuke Tanigawa, David Amar, Nina J. Mars, Matthew Aguirre, Guhan Ram Venkataraman, Michael Wainberg, Hanna M. Ollila, James P. Pirruccello, Junyang Qian, Anna Shcherbina, FinnGen, Fatima Rodriguez, Themistocles L. Assimes, Vineeta Agarwala, Robert Tibshirani, Trevor Hastie, Samuli Ripatti, Jonathan K. Pritchard, Mark J. Daly, Manuel A. Rivas

bioRxiv 660506; doi: https://doi.org/10.1101/660506

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