Smoking and blood DNA methylation: novel associations, replication of previous findings and assessment of reversibility

Pierre-Antoine Dugué; Chol-Hee Jung; JiHoon E Joo; Xiaochuan Wang; Ee Ming Wong; Enes Makalic; Daniel F Schmidt; Laura Baglietto; Gianluca Severi; Melissa C Southey; Dallas R English; Graham G Giles; Roger L Milne

doi:10.1101/660878

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Smoking and blood DNA methylation: novel associations, replication of previous findings and assessment of reversibility

Pierre-Antoine Dugué, Chol-Hee Jung, JiHoon E Joo, Xiaochuan Wang, Ee Ming Wong, Enes Makalic, Daniel F Schmidt, Laura Baglietto, Gianluca Severi, Melissa C Southey, Dallas R English, Graham G Giles, Roger L Milne

doi: https://doi.org/10.1101/660878

Pierre-Antoine Dugué

1Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

3Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia

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For correspondence: pierre-antoine.dugue@monash.edu

Chol-Hee Jung

4Melbourne Bioinformatics, The University of Melbourne, Parkville, VIC, Australia

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JiHoon E Joo

5Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia

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Xiaochuan Wang

1Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia

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Ee Ming Wong

3Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia

6Genetic Epidemiology Laboratory, Department of Clinical Pathology, University of Melbourne, VIC, Australia

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Enes Makalic

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

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Daniel F Schmidt

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

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Laura Baglietto

7Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

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Gianluca Severi

8Centre de Recherche en Epidémiologie et Santé des Populations (CESP, Inserm U1018), Facultés de Médecine Universités Paris-Saclay, UVSQ, Gustave Roussy, Villejuif, France

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Melissa C Southey

3Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia

6Genetic Epidemiology Laboratory, Department of Clinical Pathology, University of Melbourne, VIC, Australia

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Dallas R English

1Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

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Graham G Giles

1Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

3Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia

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Roger L Milne

1Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia

2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia

3Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia

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Posted June 08, 2019.

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Smoking and blood DNA methylation: novel associations, replication of previous findings and assessment of reversibility

bioRxiv 660878; doi: https://doi.org/10.1101/660878

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