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Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios
Marc J Williams, Luiz Zapata, Benjamin Werner, View ORCID ProfileChris Barnes, Andrea Sottoriva, View ORCID ProfileTrevor A Graham
doi: https://doi.org/10.1101/661264
Marc J Williams
1Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
Luiz Zapata
2Centre for Evolution and Cancer, Institute of Cancer Research, London, UK
Benjamin Werner
2Centre for Evolution and Cancer, Institute of Cancer Research, London, UK
Chris Barnes
3Department of Cell and Developmental Biology, University College London, UK
Andrea Sottoriva
2Centre for Evolution and Cancer, Institute of Cancer Research, London, UK
Trevor A Graham
1Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
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Posted June 05, 2019.
Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios
Marc J Williams, Luiz Zapata, Benjamin Werner, Chris Barnes, Andrea Sottoriva, Trevor A Graham
bioRxiv 661264; doi: https://doi.org/10.1101/661264
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