Abstract
The recent outbreaks of African swine fever (ASF) in China and Europe have threatened the swine industry globally. To control the transmission of the African swine fever virus (ASFV), we developed ASFVdb, the African swine fever virus database, an online data visualization and analysis platform for comparative genomics and proteomics. On the basis of known ASFV genes, ASFVdb reannotates the genomes of every strain and annotates 4833 possible ORFs. Moreover, ASFVdb performs a thorough analysis of the population genetics of all the published genomes of ASFV strains and performs functional and structural predictions for all genes. For each ASFV gene, visitors can obtain not only basic information of the gene but also the distribution of the gene in strains, conserved or high mutation regions, possible subcellular location of the gene and topology of the gene. In the genome browser, ASFVdb provides sliding window population genetics analysis results, which facilitate genetics and evolutional analyses at the genomic level. The web interface is constructed based on SWAV 1.0. ASFVdb is freely accessible at http://asfvdb.popgenetics.net.
Footnotes
1, Two strains, China_LN_2018 and China_HLJ_2018, have been added and the database is refresed. 2, English writing has been improved.
