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KCND3 is a novel susceptibility locus for early repolarization
View ORCID ProfileAlexander Teumer, Teresa Trenkwalder, Thorsten Kessler, Yalda Jamshidi, Marten E. van den Berg, Bernhard Kaess, Christopher P. Nelson, Rachel Bastiaenen, Marzia De Bortoli, Alessandra Rossini, Isabel Deisenhofer, Klaus Stark, Solmaz Assa, Peter S. Braund, Claudia Cabrera, Anna F. Dominiczak, Martin Gögele, Leanne M. Hall, M. Arfan Ikram, Maryam Kavousi, Karl J. Lackner, Lifelines Cohort Study, Christian Müller, Thomas Münzel, Matthias Nauck, Sandosh Padmanabhan, Norbert Pfeiffer, Tim D. Spector, Andre G. Uitterlinden, View ORCID ProfileNiek Verweij, Uwe Völker, Helen R. Warren, Mobeen Zafar, Stephan B. Felix, Jan A. Kors, Harold Snieder, Patricia B. Munroe, Cristian Pattaro, Christian Fuchsberger, Georg Schmidt, Ilja M. Nolte, Heribert Schunkert, Peter Pramstaller, Philipp S. Wild, View ORCID ProfilePim van der Harst, Bruno H. Stricker, Renate B. Schnabel, Nilesh J. Samani, Christian Hengstenberg, Marcus Dörr, Elijah R. Behr, Wibke Reinhard
doi: https://doi.org/10.1101/673640
Alexander Teumer
1Institute for Community Medicine, University Medicine Greifswald, Germany
2DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany
Teresa Trenkwalder
3Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, School of Medicine, Technical University of Munich, Munich, Germany
Thorsten Kessler
3Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, School of Medicine, Technical University of Munich, Munich, Germany
Yalda Jamshidi
4Genetics Research Centre, Institute of Molecular and Clinical Sciences, St George’s University of London, United Kingdom
Marten E. van den Berg
5Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Bernhard Kaess
6Medizinische Klinik I, St. Josefs-Hospital, Wiesbaden, Germany
Christopher P. Nelson
7Department of Cardiovascular Sciences, Cardiovascular Research Centre, Leicester, Leicester, United Kingdom
8NIHR Leicester Biomedical Research Centre University of Leicester, Leicester, United Kingdom
Rachel Bastiaenen
9Cardiology Clinial Academic Group, Institute of Molecular and Clinical Sciences, St George’s, University of London, United Kingdom
Marzia De Bortoli
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Alessandra Rossini
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Isabel Deisenhofer
3Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, School of Medicine, Technical University of Munich, Munich, Germany
Klaus Stark
11Department of Genetic Epidemiology, University Regensburg, Germany
Solmaz Assa
12Department of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands
Peter S. Braund
7Department of Cardiovascular Sciences, Cardiovascular Research Centre, Leicester, Leicester, United Kingdom
8NIHR Leicester Biomedical Research Centre University of Leicester, Leicester, United Kingdom
Claudia Cabrera
13Clinical Pharmacology, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, UK
14NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
15Centre for Translational Bioinformatics, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK
Anna F. Dominiczak
16Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
Martin Gögele
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Leanne M. Hall
7Department of Cardiovascular Sciences, Cardiovascular Research Centre, Leicester, Leicester, United Kingdom
8NIHR Leicester Biomedical Research Centre University of Leicester, Leicester, United Kingdom
M. Arfan Ikram
5Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Maryam Kavousi
5Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Karl J. Lackner
17Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
18German Center for Cardiovascular Research (DZHK), partner site RhineMain, Mainz, Germany
Christian Müller
20Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Germany, DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany
Thomas Münzel
18German Center for Cardiovascular Research (DZHK), partner site RhineMain, Mainz, Germany
21Center for Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
Matthias Nauck
2DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany
22Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
Sandosh Padmanabhan
16Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
Norbert Pfeiffer
23Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
Tim D. Spector
24Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK
Andre G. Uitterlinden
5Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Niek Verweij
12Department of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands
Uwe Völker
2DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany
25Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany
Helen R. Warren
13Clinical Pharmacology, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, UK
14NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Mobeen Zafar
12Department of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands
Stephan B. Felix
2DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany
26Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
Jan A. Kors
27Department of Medical Informatics, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Harold Snieder
28Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Patricia B. Munroe
13Clinical Pharmacology, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, UK
14NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Cristian Pattaro
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Christian Fuchsberger
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Georg Schmidt
29Innere Medizin I, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
30Deutsches Zentrum für Herz-und Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany
Ilja M. Nolte
28Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Heribert Schunkert
3Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, School of Medicine, Technical University of Munich, Munich, Germany
30Deutsches Zentrum für Herz-und Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany
Peter Pramstaller
10Institute for Biomedicine, Eurac Research, affiliated with the University of Lübeck, Bolzano, Italy
Philipp S. Wild
31Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; DZHK (German Center for Cardiovascular Research), partner site Rhine-Main, Mainz, Germany
Pim van der Harst
12Department of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands
Bruno H. Stricker
5Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, The Netherlands
Renate B. Schnabel
20Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Germany, DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany
Nilesh J. Samani
7Department of Cardiovascular Sciences, Cardiovascular Research Centre, Leicester, Leicester, United Kingdom
8NIHR Leicester Biomedical Research Centre University of Leicester, Leicester, United Kingdom
Christian Hengstenberg
32Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria
Marcus Dörr
2DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany
26Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
Elijah R. Behr
33Cardiology Clinical Academic Group, Institute of Molecular and Clinical Sciences, St George’s, University of London, United Kingdom AND St George’s University Hospitals NHS Foundation Trust, London, United Kingdom
Wibke Reinhard
3Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, School of Medicine, Technical University of Munich, Munich, Germany
Posted June 18, 2019.
KCND3 is a novel susceptibility locus for early repolarization
Alexander Teumer, Teresa Trenkwalder, Thorsten Kessler, Yalda Jamshidi, Marten E. van den Berg, Bernhard Kaess, Christopher P. Nelson, Rachel Bastiaenen, Marzia De Bortoli, Alessandra Rossini, Isabel Deisenhofer, Klaus Stark, Solmaz Assa, Peter S. Braund, Claudia Cabrera, Anna F. Dominiczak, Martin Gögele, Leanne M. Hall, M. Arfan Ikram, Maryam Kavousi, Karl J. Lackner, Lifelines Cohort Study, Christian Müller, Thomas Münzel, Matthias Nauck, Sandosh Padmanabhan, Norbert Pfeiffer, Tim D. Spector, Andre G. Uitterlinden, Niek Verweij, Uwe Völker, Helen R. Warren, Mobeen Zafar, Stephan B. Felix, Jan A. Kors, Harold Snieder, Patricia B. Munroe, Cristian Pattaro, Christian Fuchsberger, Georg Schmidt, Ilja M. Nolte, Heribert Schunkert, Peter Pramstaller, Philipp S. Wild, Pim van der Harst, Bruno H. Stricker, Renate B. Schnabel, Nilesh J. Samani, Christian Hengstenberg, Marcus Dörr, Elijah R. Behr, Wibke Reinhard
bioRxiv 673640; doi: https://doi.org/10.1101/673640
KCND3 is a novel susceptibility locus for early repolarization
Alexander Teumer, Teresa Trenkwalder, Thorsten Kessler, Yalda Jamshidi, Marten E. van den Berg, Bernhard Kaess, Christopher P. Nelson, Rachel Bastiaenen, Marzia De Bortoli, Alessandra Rossini, Isabel Deisenhofer, Klaus Stark, Solmaz Assa, Peter S. Braund, Claudia Cabrera, Anna F. Dominiczak, Martin Gögele, Leanne M. Hall, M. Arfan Ikram, Maryam Kavousi, Karl J. Lackner, Lifelines Cohort Study, Christian Müller, Thomas Münzel, Matthias Nauck, Sandosh Padmanabhan, Norbert Pfeiffer, Tim D. Spector, Andre G. Uitterlinden, Niek Verweij, Uwe Völker, Helen R. Warren, Mobeen Zafar, Stephan B. Felix, Jan A. Kors, Harold Snieder, Patricia B. Munroe, Cristian Pattaro, Christian Fuchsberger, Georg Schmidt, Ilja M. Nolte, Heribert Schunkert, Peter Pramstaller, Philipp S. Wild, Pim van der Harst, Bruno H. Stricker, Renate B. Schnabel, Nilesh J. Samani, Christian Hengstenberg, Marcus Dörr, Elijah R. Behr, Wibke Reinhard
bioRxiv 673640; doi: https://doi.org/10.1101/673640
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