Higher fitness yeast genotypes are less robust to deleterious mutations

Milo S. Johnson; Alena Martsul; Sergey Kryazhimskiy; Michael M. Desai

doi:10.1101/675314

Article Information

doi

https://doi.org/10.1101/675314

History

June 20, 2019.

The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

Milo S. Johnson1,2,3,
Alena Martsul4,
Sergey Kryazhimskiy4,† and
Michael M. Desai1,2,3,5,†,*

¹Department of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138
²Quantitative Biology Initiative, Harvard University, Cambridge MA 02138
³NSF-Simons Center for Mathematical and Statistical Analysis of Biology, Harvard University, Cambridge MA 02138
⁴Division of Biological Sciences, University of California San Diego, La Jolla CA 92093
⁵Department of Physics, Harvard University, Cambridge MA 02138