Super-resolution Imaging Reveals 3D Structure and Organizing Mechanism of Accessible Chromatin

Liangqi Xie; Peng Dong; Yifeng Qi; Margherita De Marzio; Xingqi Chen; Sambashiva Banala; Wesley R. Legant; Brian P. English; Anders S. Hansen; Anton Schulmann; Luke D. Lavis; Eric Betzig; Rafael Casellas; Howard Y. Chang; Bin Zhang; Robert Tjian; Zhe Liu

doi:10.1101/678649

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Super-resolution Imaging Reveals 3D Structure and Organizing Mechanism of Accessible Chromatin

Liangqi Xie, Peng Dong, Yifeng Qi, Margherita De Marzio, Xingqi Chen, Sambashiva Banala, Wesley R. Legant, Brian P. English, Anders S. Hansen, Anton Schulmann, Luke D. Lavis, Eric Betzig, Rafael Casellas, Howard Y. Chang, Bin Zhang, Robert Tjian, Zhe Liu

doi: https://doi.org/10.1101/678649

Liangqi Xie

2Department of Molecular and Cell Biology, Li Ka Shing Center for Biomedical and Health Sciences, CIRM Center of Excellence, University of California, Berkeley, CA 94720, USA

3Howard Hughes Medical Institute, Berkeley, CA 94720, USA

6Janelia Visitor Program, Janelia Research Campus, Ashburn, VA 20147, USA

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Peng Dong

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Yifeng Qi

4Departments of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139-4307, USA

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Margherita De Marzio

4Departments of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139-4307, USA

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Xingqi Chen

5Center for Personal Dynamic Regulomes and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA

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Sambashiva Banala

3Howard Hughes Medical Institute, Berkeley, CA 94720, USA

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Wesley R. Legant

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Brian P. English

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Anders S. Hansen

2Department of Molecular and Cell Biology, Li Ka Shing Center for Biomedical and Health Sciences, CIRM Center of Excellence, University of California, Berkeley, CA 94720, USA

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Anton Schulmann

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Luke D. Lavis

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Eric Betzig

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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Rafael Casellas

7Lymphocyte Nuclear Biology, NIAMS and Center of Cancer Research, NCI, NIH, Bethesda, MD 20892, USA

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Howard Y. Chang

5Center for Personal Dynamic Regulomes and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA

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Bin Zhang

4Departments of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139-4307, USA

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For correspondence: liuz11@janelia.hhmi.org jmlim@berkeley.edu binz@mit.edu

Robert Tjian

2Department of Molecular and Cell Biology, Li Ka Shing Center for Biomedical and Health Sciences, CIRM Center of Excellence, University of California, Berkeley, CA 94720, USA

3Howard Hughes Medical Institute, Berkeley, CA 94720, USA

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For correspondence: liuz11@janelia.hhmi.org jmlim@berkeley.edu binz@mit.edu

Zhe Liu

1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA

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For correspondence: liuz11@janelia.hhmi.org jmlim@berkeley.edu binz@mit.edu

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