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Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria
Kohta Ikegami, Stefano Secchia, Omar Almakki, Jason D. Lieb, Ivan P. Moskowitz
doi: https://doi.org/10.1101/682260
Kohta Ikegami
1Departments of Pediatrics, The University of Chicago, Chicago, Illinois, USA
3Departments of Human Genetics, The University of Chicago, Chicago, Illinois, USA
Stefano Secchia
3Departments of Human Genetics, The University of Chicago, Chicago, Illinois, USA
4Department of Biology, Lund University, Lund, Sweden
Omar Almakki
1Departments of Pediatrics, The University of Chicago, Chicago, Illinois, USA
Jason D. Lieb
3Departments of Human Genetics, The University of Chicago, Chicago, Illinois, USA
Ivan P. Moskowitz
1Departments of Pediatrics, The University of Chicago, Chicago, Illinois, USA
2Departments of Pathology, The University of Chicago, Chicago, Illinois, USA
3Departments of Human Genetics, The University of Chicago, Chicago, Illinois, USA
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Posted December 18, 2019.
Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria
Kohta Ikegami, Stefano Secchia, Omar Almakki, Jason D. Lieb, Ivan P. Moskowitz
bioRxiv 682260; doi: https://doi.org/10.1101/682260
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