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H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
View ORCID ProfileYichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman-Aiden, Shang Li, Lakshmanan Manikandan, Vinay Tergaonkar, View ORCID ProfileGreg Tucker-Kellogg, Melissa Jane Fullwood
doi: https://doi.org/10.1101/684712
Yichao Cai
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
2Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, 117558 Singapore
Ying Zhang
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
Yan Ping Loh
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
Jia Qi Tng
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
Mei Chee Lim
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
3Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, 169857 Singapore
Zhendong Cao
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
4Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA19104, USA
Anandhkumar Raju
5Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, 138673 Singapore
Erez Lieberman-Aiden
6Department of Genetics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX77030, USA
Shang Li
3Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, 169857 Singapore
7Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 2 Medical Drive,117597 Singapore
Lakshmanan Manikandan
5Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, 138673 Singapore
Vinay Tergaonkar
5Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, 138673 Singapore
Greg Tucker-Kellogg
2Department of Biological Sciences, National University of Singapore, 16 Science Drive 4, 117558 Singapore
8Computational Biology Programme, National University of Singapore, 6 Science Drive 2, 117546 Singapore
Melissa Jane Fullwood
1Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore
5Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, 138673 Singapore
9School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551 Singapore
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Posted November 06, 2020.
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman-Aiden, Shang Li, Lakshmanan Manikandan, Vinay Tergaonkar, Greg Tucker-Kellogg, Melissa Jane Fullwood
bioRxiv 684712; doi: https://doi.org/10.1101/684712
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman-Aiden, Shang Li, Lakshmanan Manikandan, Vinay Tergaonkar, Greg Tucker-Kellogg, Melissa Jane Fullwood
bioRxiv 684712; doi: https://doi.org/10.1101/684712
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