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Loss of adaptive capacity in asthmatics revealed by biomarker fluctuation dynamics upon experimental rhinovirus challenge

View ORCID ProfileAnirban Sinha, René Lutter, Binbin Xu, Tamara Dekker, Barbara Dierdorp, Peter J. Sterk, Urs Frey, Edgar Delgado-Eckert
doi: https://doi.org/10.1101/684910
Anirban Sinha
aAmsterdam UMC, University of Amsterdam, Department of Respiratory Medicine, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
bAmsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
cUniversity of Basel, University Children’s Hospital (UKBB), Spitalstrasse 33, Postfach, 4031 Basel, Switzerland
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  • ORCID record for Anirban Sinha
  • For correspondence: a.sinha@amc.uva.nl anirban.sinha@ukbb.ch
René Lutter
aAmsterdam UMC, University of Amsterdam, Department of Respiratory Medicine, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
bAmsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
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Binbin Xu
dUniversity of Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, F-33000 Bordeaux, France
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Tamara Dekker
bAmsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
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Barbara Dierdorp
bAmsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
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Peter J. Sterk
aAmsterdam UMC, University of Amsterdam, Department of Respiratory Medicine, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
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Urs Frey
cUniversity of Basel, University Children’s Hospital (UKBB), Spitalstrasse 33, Postfach, 4031 Basel, Switzerland
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Edgar Delgado-Eckert
cUniversity of Basel, University Children’s Hospital (UKBB), Spitalstrasse 33, Postfach, 4031 Basel, Switzerland
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Article Information

doi 
https://doi.org/10.1101/684910
History 
  • July 2, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Anirban Sinhaa,b,c,1,
  2. René Luttera,b,
  3. Binbin Xud,
  4. Tamara Dekkerb,
  5. Barbara Dierdorpb,
  6. Peter J. Sterka,
  7. Urs Freyc and
  8. Edgar Delgado-Eckertc
  1. aAmsterdam UMC, University of Amsterdam, Department of Respiratory Medicine, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
  2. bAmsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
  3. cUniversity of Basel, University Children’s Hospital (UKBB), Spitalstrasse 33, Postfach, 4031 Basel, Switzerland
  4. dUniversity of Bordeaux, Inserm, Bordeaux Population Health Research Center, UMR 1219, F-33000 Bordeaux, France
  1. ↵1Corresponding author. Email: a.sinha{at}amc.uva.nl, anirban.sinha{at}ukbb.ch, Phone: +31 20 566 4356
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Posted July 02, 2019.
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Loss of adaptive capacity in asthmatics revealed by biomarker fluctuation dynamics upon experimental rhinovirus challenge
Anirban Sinha, René Lutter, Binbin Xu, Tamara Dekker, Barbara Dierdorp, Peter J. Sterk, Urs Frey, Edgar Delgado-Eckert
bioRxiv 684910; doi: https://doi.org/10.1101/684910
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Loss of adaptive capacity in asthmatics revealed by biomarker fluctuation dynamics upon experimental rhinovirus challenge
Anirban Sinha, René Lutter, Binbin Xu, Tamara Dekker, Barbara Dierdorp, Peter J. Sterk, Urs Frey, Edgar Delgado-Eckert
bioRxiv 684910; doi: https://doi.org/10.1101/684910

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