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Molecular estimation of neurodegeneration pseudotime in older brains

Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K Greenwood, Solveig K Sieberts, Phillip L De Jager, Nilufer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, View ORCID ProfileBenjamin A Logsdon
doi: https://doi.org/10.1101/686824
Sumit Mukherjee
1Sage Bionetworks, Seattle, WA, USA
2Microsoft, Redmond, WA, USA
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Laura Heath
1Sage Bionetworks, Seattle, WA, USA
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Christoph Preuss
3The Jackson Laboratory, Bar Harbor, ME, USA
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Suman Jayadev
4Department of Neurology, University of Washington, Seattle, WA, USA
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Gwenn A. Garden
4Department of Neurology, University of Washington, Seattle, WA, USA
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Anna K Greenwood
1Sage Bionetworks, Seattle, WA, USA
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Solveig K Sieberts
1Sage Bionetworks, Seattle, WA, USA
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Phillip L De Jager
5Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York City, USA
6Taub Institute, Columbia University Irving Medical Center, New York City, USA
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Nilufer Ertekin-Taner
7Mayo Clinic Florida, Department of Neurology, Jacksonville, FL, USA
8Mayo Clinic Florida, Department of Neuroscience, Jacksonville, FL, USA
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Gregory W Carter
3The Jackson Laboratory, Bar Harbor, ME, USA
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Lara M Mangravite
1Sage Bionetworks, Seattle, WA, USA
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Benjamin A Logsdon
1Sage Bionetworks, Seattle, WA, USA
9Cajal Neuroscience, Seattle, WA, USA
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  • ORCID record for Benjamin A Logsdon
  • For correspondence: ben@cajalneuro.com
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Article Information

doi 
https://doi.org/10.1101/686824
History 
  • October 23, 2020.

Article Versions

  • Version 1 (June 28, 2019 - 16:56).
  • Version 2 (June 30, 2019 - 16:13).
  • Version 3 (July 20, 2020 - 19:31).
  • You are viewing Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Sumit Mukherjee1,2,*,†,
  2. Laura Heath1,*,
  3. Christoph Preuss3,
  4. Suman Jayadev4,
  5. Gwenn A. Garden4,
  6. Anna K Greenwood1,
  7. Solveig K Sieberts1,
  8. Phillip L De Jager5,6,
  9. Nilufer Ertekin-Taner7,8,
  10. Gregory W Carter3,
  11. Lara M Mangravite1 and
  12. Benjamin A Logsdon1,9,10,†
  1. 1Sage Bionetworks, Seattle, WA, USA
  2. 2Microsoft, Redmond, WA, USA
  3. 3The Jackson Laboratory, Bar Harbor, ME, USA
  4. 4Department of Neurology, University of Washington, Seattle, WA, USA
  5. 5Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York City, USA
  6. 6Taub Institute, Columbia University Irving Medical Center, New York City, USA
  7. 7Mayo Clinic Florida, Department of Neurology, Jacksonville, FL, USA
  8. 8Mayo Clinic Florida, Department of Neuroscience, Jacksonville, FL, USA
  9. 9Cajal Neuroscience, Seattle, WA, USA
  1. ↵10Correspondence: Benjamin A Logsdon, PhD, Cajal Neuroscience, 1616 Eastlake Ave E #208, Seattle, WA 98102, ben{at}cajalneuro.com
  1. ↵* These authors contributed equally to this work.

  • ↵† Current Address.

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Molecular estimation of neurodegeneration pseudotime in older brains
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K Greenwood, Solveig K Sieberts, Phillip L De Jager, Nilufer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, Benjamin A Logsdon
bioRxiv 686824; doi: https://doi.org/10.1101/686824
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Molecular estimation of neurodegeneration pseudotime in older brains
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K Greenwood, Solveig K Sieberts, Phillip L De Jager, Nilufer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, Benjamin A Logsdon
bioRxiv 686824; doi: https://doi.org/10.1101/686824

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