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A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data

View ORCID ProfileShamus M. Cooley, View ORCID ProfileTimothy Hamilton, View ORCID ProfileJ. Christian J. Ray, View ORCID ProfileEric J. Deeds
doi: https://doi.org/10.1101/689851
Shamus M. Cooley
1Interdepartmental Program for Bioinformatics, University of California – Los Angeles
3Institute for Quantitative and Computational Biosciences, University of California – Los Angeles
4Center for Computational Biology, University of Kansas – Lawrence
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  • ORCID record for Shamus M. Cooley
Timothy Hamilton
2Department of Integrative Biology and Physiology, University of California – Los Angeles
3Institute for Quantitative and Computational Biosciences, University of California – Los Angeles
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  • ORCID record for Timothy Hamilton
J. Christian J. Ray
4Center for Computational Biology, University of Kansas – Lawrence
5Department of Molecular Biosciences, University of Kansas – Lawrence
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  • For correspondence: deeds@ucla.edu jjray@ku.edu
Eric J. Deeds
2Department of Integrative Biology and Physiology, University of California – Los Angeles
3Institute for Quantitative and Computational Biosciences, University of California – Los Angeles
4Center for Computational Biology, University of Kansas – Lawrence
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  • For correspondence: deeds@ucla.edu jjray@ku.edu
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Article Information

doi 
https://doi.org/10.1101/689851
History 
  • September 28, 2020.

Article Versions

  • Version 1 (July 2, 2019 - 08:37).
  • Version 2 (July 12, 2019 - 21:26).
  • Version 3 (November 14, 2019 - 14:26).
  • You are currently viewing Version 4 of this article (September 28, 2020 - 21:25).
  • Version 5 (January 7, 2022 - 00:48).
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Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Shamus M. Cooley1,3,4,
  2. Timothy Hamilton2,3,
  3. J. Christian J. Ray4,5,* and
  4. Eric J. Deeds2,3,4,*
  1. 1Interdepartmental Program for Bioinformatics, University of California – Los Angeles
  2. 2Department of Integrative Biology and Physiology, University of California – Los Angeles
  3. 3Institute for Quantitative and Computational Biosciences, University of California – Los Angeles
  4. 4Center for Computational Biology, University of Kansas – Lawrence
  5. 5Department of Molecular Biosciences, University of Kansas – Lawrence
  1. ↵*Corresponding authors: EJD (deeds{at}ucla.edu) and JCJR (jjray{at}ku.edu).
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Posted September 28, 2020.
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A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data
Shamus M. Cooley, Timothy Hamilton, J. Christian J. Ray, Eric J. Deeds
bioRxiv 689851; doi: https://doi.org/10.1101/689851
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A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data
Shamus M. Cooley, Timothy Hamilton, J. Christian J. Ray, Eric J. Deeds
bioRxiv 689851; doi: https://doi.org/10.1101/689851

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