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Massively parallel kinetic profiling of natural and engineered CRISPR nucleases

View ORCID ProfileStephen K. Jones Jr, John A. Hawkins, Nicole V. Johnson, Cheulhee Jung, Kuang Hu, View ORCID ProfileJames R. Rybarski, Janice S. Chen, Jennifer A. Doudna, View ORCID ProfileWilliam H. Press, View ORCID ProfileIlya J. Finkelstein
doi: https://doi.org/10.1101/696393
Stephen K. Jones Jr
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
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  • ORCID record for Stephen K. Jones Jr
John A. Hawkins
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
4Oden Institute for Computational Engineering and Science, University of Texas at Austin, Austin, Texas 78712, USA
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Nicole V. Johnson
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
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Cheulhee Jung
5Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea
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Kuang Hu
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
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James R. Rybarski
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
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  • ORCID record for James R. Rybarski
Janice S. Chen
6Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, United States
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Jennifer A. Doudna
6Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, United States
7University of California, Chemistry, Berkeley, CA
8Howard Hughes Medical Institute, University of California, Berkeley, CA
9Lawrence Berkeley National Laboratory, Physical Biosciences Division, Berkeley, CA
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William H. Press
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
4Oden Institute for Computational Engineering and Science, University of Texas at Austin, Austin, Texas 78712, USA
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Ilya J. Finkelstein
1Department of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA
2Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
3Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, USA
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  • ORCID record for Ilya J. Finkelstein
  • For correspondence: ifinkelstein@cm.utexas.edu
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Posted July 09, 2019.
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Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
Stephen K. Jones Jr, John A. Hawkins, Nicole V. Johnson, Cheulhee Jung, Kuang Hu, James R. Rybarski, Janice S. Chen, Jennifer A. Doudna, William H. Press, Ilya J. Finkelstein
bioRxiv 696393; doi: https://doi.org/10.1101/696393
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Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
Stephen K. Jones Jr, John A. Hawkins, Nicole V. Johnson, Cheulhee Jung, Kuang Hu, James R. Rybarski, Janice S. Chen, Jennifer A. Doudna, William H. Press, Ilya J. Finkelstein
bioRxiv 696393; doi: https://doi.org/10.1101/696393

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