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Genetic rescue without genomic swamping in wild populations

View ORCID ProfileSarah W. Fitzpatrick, View ORCID ProfileGideon S. Bradburd, View ORCID ProfileColin T. Kremer, Patricia E. Salerno, View ORCID ProfileLisa M. Angeloni, View ORCID ProfileW. Chris Funk
doi: https://doi.org/10.1101/701706
Sarah W. Fitzpatrick
1W.K. Kellogg Biological Station, Michigan State University, 3700 E. Gull Lake Dr., Hickory Corners, MI 49060
2Department of Integrative Biology, Michigan State University, East Lansing, MI
3Ecology, Evolutionary Biology, & Behavior Program, Michigan State University, East Lansing, MI
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  • For correspondence: sfitz@msu.edu
Gideon S. Bradburd
2Department of Integrative Biology, Michigan State University, East Lansing, MI
3Ecology, Evolutionary Biology, & Behavior Program, Michigan State University, East Lansing, MI
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Colin T. Kremer
1W.K. Kellogg Biological Station, Michigan State University, 3700 E. Gull Lake Dr., Hickory Corners, MI 49060
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Patricia E. Salerno
4Department of Biology, 1878 Campus Delivery, Colorado State University, Fort Collins, Colorado 80523
5Museo de Zoología, Escuela de Biología, Pontificia Universidad Católica del Ecuador, Quito, Ecuador
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Lisa M. Angeloni
4Department of Biology, 1878 Campus Delivery, Colorado State University, Fort Collins, Colorado 80523
6Graduate Degree Program in Ecology, Colorado State University, Fort Collins, CO 80523
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W. Chris Funk
4Department of Biology, 1878 Campus Delivery, Colorado State University, Fort Collins, Colorado 80523
6Graduate Degree Program in Ecology, Colorado State University, Fort Collins, CO 80523
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Abstract

Gene flow is an enigmatic evolutionary force because it can limit adaptation but can also help populations escape inbreeding depression. Manipulating gene flow for conservation purposes is a controversial, but potentially powerful management strategy. We use multigenerational pedigrees and genomics to test demographic and evolutionary consequences of manipulating gene flow in two isolated wild Trinidadian guppy populations. We found that on average, hybrids lived longer and reproduced more. Despite overall genome-wide homogenization, alleles potentially associated with local adaptation were not entirely swamped by gene flow. Our results suggest that combining new genomic variation from immigrants with potentially adaptive variation from the recipient population resulted in highly fit hybrids and subsequent increases in population size. Contrary to the prevailing view that gene flow constrains adaptation, our study shows that immigration can produce long-term fitness benefits in small populations without swamping locally adaptive variation.

Footnotes

  • https://github.com/ctkremer/guppy

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted July 15, 2019.
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Genetic rescue without genomic swamping in wild populations
Sarah W. Fitzpatrick, Gideon S. Bradburd, Colin T. Kremer, Patricia E. Salerno, Lisa M. Angeloni, W. Chris Funk
bioRxiv 701706; doi: https://doi.org/10.1101/701706
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Genetic rescue without genomic swamping in wild populations
Sarah W. Fitzpatrick, Gideon S. Bradburd, Colin T. Kremer, Patricia E. Salerno, Lisa M. Angeloni, W. Chris Funk
bioRxiv 701706; doi: https://doi.org/10.1101/701706

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