PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

Mélissa Léveillé; Aurèle Besse-Patin; Nathalie Jouvet; Stewart Jeromson; Naveen P. Khan; Sarah Sczelecki; Cindy Baldwin; Annie Dumouchel; Jorge Correia; Paulo Jannig; Stephanie K. Petrillo; Anthoula Lazaris; Jonathan Boulais; Peter Metrakos; Jorge L. Ruas; Jennifer L. Estall

doi:10.1101/703678

New Results

PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

Mélissa Léveillé, Aurèle Besse-Patin, Nathalie Jouvet, Stewart Jeromson, Naveen P. Khan, Sarah Sczelecki, Cindy Baldwin, Annie Dumouchel, Jorge Correia, Paulo Jannig, Stephanie K. Petrillo, Anthoula Lazaris, Jonathan Boulais, Peter Metrakos, Jorge L. Ruas, View ORCID ProfileJennifer L. Estall

doi: https://doi.org/10.1101/703678

Mélissa Léveillé

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

2Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Aurèle Besse-Patin

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

2Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Nathalie Jouvet

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stewart Jeromson

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

3Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Naveen P. Khan

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

3Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sarah Sczelecki

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

3Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Cindy Baldwin

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Annie Dumouchel

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jorge Correia

5Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Paulo Jannig

5Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stephanie K. Petrillo

4Cancer Research Program, Department of Surgery, McGill University Health Center-Research Institute, Montreal, Quebec, H4A 3J1, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Anthoula Lazaris

4Cancer Research Program, Department of Surgery, McGill University Health Center-Research Institute, Montreal, Quebec, H4A 3J1, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jonathan Boulais

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Peter Metrakos

4Cancer Research Program, Department of Surgery, McGill University Health Center-Research Institute, Montreal, Quebec, H4A 3J1, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jorge L. Ruas

5Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jennifer L. Estall

1Institut de recherches cliniques de Montreal (IRCM), Montreal, Quebec, Canada

2Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

3Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Jennifer L. Estall
For correspondence: jennifer.estall@ircm.qc.ca

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

Supplemental file 1[supplements/703678_file03.xlsx]
Supplemental file 2[supplements/703678_file04.xlsx]
Supplemental file 3[supplements/703678_file05.xlsx]
Supplemental file 4[supplements/703678_file06.xlsx]

View the discussion thread.

PreviousNext

Posted July 16, 2019.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

bioRxiv 703678; doi: https://doi.org/10.1101/703678

Share This Article:

Citation Tools

PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

bioRxiv 703678; doi: https://doi.org/10.1101/703678

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Molecular Biology

Subject Areas

All Articles

Animal Behavior and Cognition (4224)
Biochemistry (9101)
Bioengineering (6749)
Bioinformatics (23935)
Biophysics (12086)
Cancer Biology (9491)
Cell Biology (13728)
Clinical Trials (138)
Developmental Biology (7614)
Ecology (11656)
Epidemiology (2066)
Evolutionary Biology (15476)
Genetics (10615)
Genomics (14292)
Immunology (9456)
Microbiology (22773)
Molecular Biology (9069)
Neuroscience (48840)
Paleontology (354)
Pathology (1479)
Pharmacology and Toxicology (2562)
Physiology (3822)
Plant Biology (8307)
Scientific Communication and Education (1467)
Synthetic Biology (2289)
Systems Biology (6170)
Zoology (1297)