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Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth-cohort
View ORCID ProfileMaxwell L. Elliott, Daniel W. Belsky, Annchen R. Knodt, David Ireland, Tracy R. Melzer, Richie Poulton, Sandhya Ramrakha, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri
doi: https://doi.org/10.1101/712851
Maxwell L. Elliott
1Department of Psychology & Neuroscience, Duke University Box 104410, Durham, NC 27708, USA
Daniel W. Belsky
2Department of Epidemiology, Columbia University Mailman School of Public Health, United States
3Robert N. Butler Columbia Aging Center, Columbia University, United States
Annchen R. Knodt
1Department of Psychology & Neuroscience, Duke University Box 104410, Durham, NC 27708, USA
David Ireland
4Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, 163 Union St E, Dunedin, 9016, NZ
Tracy R. Melzer
5New Zealand Brain Research Institute, Christchurch, New Zealand
6Department of Medicine, University of Otago, Christchurch, New Zealand
Richie Poulton
4Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, 163 Union St E, Dunedin, 9016, NZ
Sandhya Ramrakha
4Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, 163 Union St E, Dunedin, 9016, NZ
Avshalom Caspi
1Department of Psychology & Neuroscience, Duke University Box 104410, Durham, NC 27708, USA
7Social, Genetic, & Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
8Department of Psychiatry & Behavioral Sciences, Duke University School of Medicine, Durham, NC 27708, USA
9Center for Genomic and Computational Biology, Duke University Box 90338, Durham, NC 27708, USA
Terrie E. Moffitt
1Department of Psychology & Neuroscience, Duke University Box 104410, Durham, NC 27708, USA
7Social, Genetic, & Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
8Department of Psychiatry & Behavioral Sciences, Duke University School of Medicine, Durham, NC 27708, USA
9Center for Genomic and Computational Biology, Duke University Box 90338, Durham, NC 27708, USA
Ahmad R. Hariri
1Department of Psychology & Neuroscience, Duke University Box 104410, Durham, NC 27708, USA
Posted July 26, 2019.
Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth-cohort
Maxwell L. Elliott, Daniel W. Belsky, Annchen R. Knodt, David Ireland, Tracy R. Melzer, Richie Poulton, Sandhya Ramrakha, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri
bioRxiv 712851; doi: https://doi.org/10.1101/712851
Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth-cohort
Maxwell L. Elliott, Daniel W. Belsky, Annchen R. Knodt, David Ireland, Tracy R. Melzer, Richie Poulton, Sandhya Ramrakha, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri
bioRxiv 712851; doi: https://doi.org/10.1101/712851
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