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Modeling predicts that CRISPR-based activators, unlike CRISPR-based repressors, scale well with increasing gRNA competition and dCas9 bottlenecking

View ORCID ProfileSamuel Clamons, View ORCID ProfileRichard Murray
doi: https://doi.org/10.1101/719278
Samuel Clamons
Caltech, Pasadena, CA, United States
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  • For correspondence: sclamons@gmail.com
Richard Murray
Caltech, Pasadena, CA, United States
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Posted August 13, 2019.
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Modeling predicts that CRISPR-based activators, unlike CRISPR-based repressors, scale well with increasing gRNA competition and dCas9 bottlenecking
Samuel Clamons, Richard Murray
bioRxiv 719278; doi: https://doi.org/10.1101/719278
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Modeling predicts that CRISPR-based activators, unlike CRISPR-based repressors, scale well with increasing gRNA competition and dCas9 bottlenecking
Samuel Clamons, Richard Murray
bioRxiv 719278; doi: https://doi.org/10.1101/719278

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