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Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk
View ORCID ProfileAnil P.S. Ori, Loes M. Olde Loohuis, Jerry Guintivano, Eilis Hannon, Emma Dempster, David St. Clair, Nick J Bass, Andrew McQuillin, Jonathan Mill, Patrick F Sullivan, Rene S. Kahn, Steve Horvath, Roel A. Ophoff
doi: https://doi.org/10.1101/727859
Anil P.S. Ori
1University of California Los Angeles, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
2Department of Genetics, University Medical Center Groningen, The Netherlands
3Department of Psychiatry, University Medical Center Groningen, The Netherlands
Loes M. Olde Loohuis
1University of California Los Angeles, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
Jerry Guintivano
4University of North Carolina, Department of Genetics, Chapel Hill, NC, US
Eilis Hannon
5University of Exeter, University of Exeter Medical School, Exeter, UK
Emma Dempster
5University of Exeter, University of Exeter Medical School, Exeter, UK
David St. Clair
6University of Aberdeen, Institute of Medical Sciences, Aberdeen, Scotland, UK
Nick J Bass
7University College London, Division of Psychiatry, UK
Andrew McQuillin
7University College London, Division of Psychiatry, UK
Jonathan Mill
5University of Exeter, University of Exeter Medical School, Exeter, UK
Patrick F Sullivan
4University of North Carolina, Department of Genetics, Chapel Hill, NC, US
9Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
Rene S. Kahn
10Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, USA
Steve Horvath
11University of California Los Angeles, Department of Biostatistics, Fielding School of Public Health, Los Angeles, CA, USA
12University of California Los Angeles, Department of Human Genetics, David Geffen School of Medicine, Los Angeles, CA, USA
Roel A. Ophoff
1University of California Los Angeles, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
12University of California Los Angeles, Department of Human Genetics, David Geffen School of Medicine, Los Angeles, CA, USA
13Erasmus University Medical Center, Department of Psychiatry, Rotterdam, The Netherlands
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Posted February 23, 2021.
Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk
Anil P.S. Ori, Loes M. Olde Loohuis, Jerry Guintivano, Eilis Hannon, Emma Dempster, David St. Clair, Nick J Bass, Andrew McQuillin, Jonathan Mill, Patrick F Sullivan, Rene S. Kahn, Steve Horvath, Roel A. Ophoff
bioRxiv 727859; doi: https://doi.org/10.1101/727859
Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk
Anil P.S. Ori, Loes M. Olde Loohuis, Jerry Guintivano, Eilis Hannon, Emma Dempster, David St. Clair, Nick J Bass, Andrew McQuillin, Jonathan Mill, Patrick F Sullivan, Rene S. Kahn, Steve Horvath, Roel A. Ophoff
bioRxiv 727859; doi: https://doi.org/10.1101/727859
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