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An Osteocalcin-deficient mouse strain without endocrine abnormalities

Cassandra R. Diegel, Steven Hann, Ugur M. Ayturk, View ORCID ProfileJennifer C.W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, View ORCID ProfileIsaac Izaguirre, VARI Vivarium and Transgenics Core, Noorulain Paracha, View ORCID ProfileBohdan Pidhaynyy, View ORCID ProfileTerry L. Dowd, Alexander G. Robling, Matthew L. Warman, View ORCID ProfileBart O. Williams
doi: https://doi.org/10.1101/732800
Cassandra R. Diegel
1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
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Steven Hann
4Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115
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Ugur M. Ayturk
4Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115
5Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, NY 10021
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Jennifer C.W. Hu
4Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115
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  • ORCID record for Jennifer C.W. Hu
Kyung-eun Lim
6Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 46202
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Casey J. Droscha
1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
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Zachary B. Madaj
2Bioinformatics and Biostatistics Core, Van Andel Research Institute, Grand Rapids, MI 49503
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Gabrielle E. Foxa
1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
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Isaac Izaguirre
1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
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  • ORCID record for Isaac Izaguirre
3Vivarium and Transgenics Core, Van Andel Research Institute, Grand Rapids, MI 49503
Noorulain Paracha
8Department of Biology, Brooklyn College, Brooklyn, NY
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Bohdan Pidhaynyy
8Department of Biology, Brooklyn College, Brooklyn, NY
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  • ORCID record for Bohdan Pidhaynyy
Terry L. Dowd
7Department of Chemistry, Brooklyn College, Brooklyn, NY
9Ph.D. Program in Chemistry and Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016
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Alexander G. Robling
6Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 46202
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Matthew L. Warman
4Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115
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Bart O. Williams
1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
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  • ORCID record for Bart O. Williams
  • For correspondence: bart.williams@vai.org
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Article Information

doi 
https://doi.org/10.1101/732800
History 
  • August 13, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Cassandra R. Diegel1,
  2. Steven Hann4,
  3. Ugur M. Ayturk4,5,
  4. Jennifer C.W. Hu4,
  5. Kyung-eun Lim6,
  6. Casey J. Droscha1,
  7. Zachary B. Madaj2,
  8. Gabrielle E. Foxa1,
  9. Isaac Izaguirre1,
  10. VARI Vivarium and Transgenics Core3,
  11. Noorulain Paracha8,
  12. Bohdan Pidhaynyy8,
  13. Terry L. Dowd7,9,
  14. Alexander G. Robling6,10,
  15. Matthew L. Warman4,10 and
  16. Bart O. Williams1,10,*
  1. 1Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503
  2. 2Bioinformatics and Biostatistics Core, Van Andel Research Institute, Grand Rapids, MI 49503
  3. 3Vivarium and Transgenics Core, Van Andel Research Institute, Grand Rapids, MI 49503
  4. 4Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115
  5. 5Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, NY 10021
  6. 6Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 46202
  7. 7Department of Chemistry, Brooklyn College, Brooklyn, NY
  8. 8Department of Biology, Brooklyn College, Brooklyn, NY
  9. 9Ph.D. Program in Chemistry and Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, NY 10016
  1. ↵*Corresponding author: email: bart.williams{at}vai.org
  1. ↵10 These authors’ laboratories contributed equally to this work.

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Posted August 13, 2019.
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An Osteocalcin-deficient mouse strain without endocrine abnormalities
Cassandra R. Diegel, Steven Hann, Ugur M. Ayturk, Jennifer C.W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, VARI Vivarium and Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexander G. Robling, Matthew L. Warman, Bart O. Williams
bioRxiv 732800; doi: https://doi.org/10.1101/732800
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An Osteocalcin-deficient mouse strain without endocrine abnormalities
Cassandra R. Diegel, Steven Hann, Ugur M. Ayturk, Jennifer C.W. Hu, Kyung-eun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, VARI Vivarium and Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexander G. Robling, Matthew L. Warman, Bart O. Williams
bioRxiv 732800; doi: https://doi.org/10.1101/732800

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